Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.50 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | PHGDH | O43175 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3103776 | 0.82 | FFAR1 (0.63) | FFAR1ALDH1A1GAACTSBELANE | |
| SCHEMBL11084513 | 0.80 | FFAR1 (0.61) | FFAR1ALDH1A1GAACTSBELANE | |
| SCHEMBL8676125 | 0.79 | FFAR1 (0.65) | FFAR1ALDH1A1GAACTSBELANE | |
| SCHEMBL3892694 | 0.77 | FFAR1 (0.57) | FFAR1ALDH1A1GAACTSBELANE | |
| SCHEMBL991241 | 0.77 | FFAR1 (0.68) | FFAR1ALDH1A1GAACTSBELANE | |
| SCHEMBL74365 | 0.76 | FFAR1 (1.00) | FFAR1ALDH1A1GAACTSBELANE | |
| SCHEMBL17285630 | 0.75 | FFAR1 (0.65) | FFAR1ALDH1A1GAACTSBELANE | |
| SCHEMBL1286277 | 0.75 | FFAR1 (0.65) | FFAR1ALDH1A1GAACTSBELANE | |
| SCHEMBL1660160 | 0.75 | FFAR1 (0.65) | FFAR1ALDH1A1GAACTSBELANE | |
| SCHEMBL883102 | 0.75 | FFAR1 (0.65) | FFAR1ALDH1A1GAACTSBELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8927717-B1 | Thiochromeno[2,3-c]quinolin-12-one derivatives, preparation method and application thereof | NATIONAL DEFENSE MEDICAL CENTER (TW) | 2015-01-06 | — | — | US | disclosed |