Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | KIT | P10721 | 12/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14741829 | 0.89 | KIT (0.49) | MAPTTP53KITTHRBMEN1 | |
| SCHEMBL14750981 | 0.85 | MAPT (0.52) | MAPTTP53KITTHRBMEN1 | |
| SCHEMBL16376138 | 0.82 | MAPT (0.54) | MAPTTP53KITTHRBMEN1 | |
| SCHEMBL14757474 | 0.82 | MAPT (0.59) | MAPTTP53KITTHRBMEN1 | |
| SCHEMBL16367710 | 0.79 | MAPT (0.51) | MAPTTP53KITTHRBMEN1 | |
| SCHEMBL16367709 | 0.78 | MAPT (0.57) | MAPTTP53THRBMEN1USP2 | |
| SCHEMBL14741563 | 0.76 | KIT (0.72) | KIT | |
| SCHEMBL14741726 | 0.76 | KIT (0.70) | KIT | |
| SCHEMBL14741741 | 0.75 | MAPT (0.48) | MAPTTP53THRBMAPK1KMT2A | |
| SCHEMBL14741471 | 0.75 | KIT (0.64) | KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150011508-A1 | COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS | IRM LLC (BM) | 2015-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150011508-A1 | COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS | KIT, PDGFRA, PDGFRB | MAPT 3899/4885TP53 388/4885KIT 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.