SCHEMBL16377239

SCHEMBL16377239

CCCCCc1ccc(-c2cc(F)c(C(F)(F)Oc3ccc(F)c(F)c3)c(F)c2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 9/20 0.45
RARA P10276 2/20 0.45
RARG P13631 1/20 0.45
THRB P10828 1/20 0.38
GCGR P47871 1/20 0.38
TSHR P16473 1/20 0.37
HSD17B10 Q99714 1/20 0.37
MEN1 O00255 2/20 0.36
ALDH1A1 P00352 2/20 0.36
KMT2A Q03164 2/20 0.36
MAPT P10636 2/20 0.36
MTOR P42345 1/20 0.36
USP2 O75604 1/20 0.36
LMNA P02545 1/20 0.36
CYP3A4 P08684 1/20 0.36
MAPK1 P28482 1/20 0.36
CASP1 P29466 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
SLCO1B3 Q9NPD5 1/20 0.36
SLCO1B1 Q9Y6L6 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16258077 0.96 RARB (0.41) RARBRARARARGTHRBGCGR
SCHEMBL12625501 0.96 RARB (0.42) RARBRARARARGTHRBGCGR
SCHEMBL12623732 0.95 RARB (0.48) RARBRARARARGTHRBGCGR
SCHEMBL12624743 0.94 RARB (0.44) RARBRARARARGTHRBGCGR
SCHEMBL12623723 0.94 RARB (0.44) RARBRARARARGTHRBGCGR
SCHEMBL12623733 0.94 RARB (0.46) RARBRARARARGTHRBGCGR
SCHEMBL12624746 0.94 RARB (0.46) RARBRARARARGGCGRTSHR
SCHEMBL12623736 0.93 RARB (0.44) RARBRARARARGTHRBGCGR
SCHEMBL12624759 0.93 RARB (0.44) RARBRARARARGTHRBGCGR
SCHEMBL12625502 0.92 RARB (0.44) RARBRARARARGTHRBGCGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9828549-B2 Liquid crystal composition, liquid crystal display device, and liquid crystal display DIC CORPORATION (JP) 2017-11-28 US disclosed
US-9822304-B2 Liquid crystal composition and liquid crystal display element containing the same DIC CORPORATION (JP) 2017-11-21 US disclosed
EP-2837670-B1 FLUOROBIPHENYL-CONTAINING COMPOSITION DAINIPPON INK & CHEMICALS (JP) 2017-09-27 EP disclosed
US-20170210986-A1 LIQUID CRYSTAL DISPLAY ELEMENT DIC CORPORATION (JP) 2017-07-27 US disclosed
US-9688913-B2 Liquid crystal composition, liquid crystal display device, and liquid crystal display DIC CORPORATION (JP) 2017-06-27 US disclosed
US-9650572-B2 Liquid crystal composition, liquid crystal display device, and liquid crystal display DIC CORPORATION (JP) 2017-05-16 US disclosed
US-9580654-B2 Liquid crystal composition and liquid crystal display device using the same DIC CORPORATION (JP) 2017-02-28 US disclosed
US-9518221-B2 Nematic liquid crystal composition and liquid crystal display device using the same DIC CORPORATION (JP) 2016-12-13 US disclosed
US-9464230-B2 Liquid crystal composition and liquid crystal display element using same DIC CORPORATION (JP) 2016-10-11 US disclosed
US-9441160-B2 Fluorobiphenyl-containing composition DIC CORPORATION (JP) 2016-09-13 US disclosed
US-20150307780-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME DIC CORPORATION (JP) 2015-10-29 US disclosed
US-20150291881-A1 FLUOROBIPHENYL-CONTAINING COMPOSITION DIC CORPORATION (JP) 2015-10-15 US disclosed
US-20150252263-A1 FLUOROBIPHENYL-CONTAINING COMPOSITION DIC CORPORATION (JP) 2015-09-10 US disclosed
US-20150252262-A1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2015-09-10 US disclosed
US-20150240158-A1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME DIC CORPORATION (JP) 2015-08-27 US disclosed
US-20150225648-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING SAME DIC CORPORATION (JP) 2015-08-13 US disclosed
US-20150108403-A1 Liquid crystal composition and liquid crystal display element DIC CORPORATION (JP) 2015-04-23 US disclosed
US-20150053891-A1 FLUOROBIPHENYL-CONTAINING COMPOSITION DIC CORPORATION (JP) 2015-02-26 US disclosed
EP-2837670-A1 FLUOROBIPHENYL-CONTAINING COMPOSITION DIC Corporation (JP) 2015-02-18 EP disclosed
US-20150001444-A1 NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING SAME DIC CORPORATION (JP) 2015-01-01 US disclosed