Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7961429 | 0.88 | BACE1 (0.54) | BACE1CTSD | |
| SCHEMBL12244786 | 0.88 | BACE1 (0.56) | BACE1CTSD | |
| SCHEMBL7950588 | 0.87 | BACE1 (0.53) | BACE1CTSD | |
| SCHEMBL1822764 | 0.86 | BACE1 (0.61) | BACE1CTSD | |
| SCHEMBL12244782 | 0.85 | BACE1 (0.61) | BACE1CTSD | |
| SCHEMBL7960035 | 0.84 | BACE1 (0.53) | BACE1CTSD | |
| SCHEMBL7954532 | 0.84 | BACE1 (0.53) | BACE1CTSD | |
| SCHEMBL7958721 | 0.84 | BACE1 (0.53) | BACE1CTSD | |
| SCHEMBL7958629 | 0.84 | BACE1 (0.54) | BACE1CTSD | |
| SCHEMBL1824211 | 0.84 | BACE1 (0.58) | BACE1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8921359-B2 | Inhibitors of beta-secretase | VITAE PHARMACEUTICALS, INC. (US) | 2014-12-30 | — | — | US | disclosed |