SCHEMBL1637859

SCHEMBL1637859

Cc1cc(Cl)[c]cc1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2342620 0.81
SCHEMBL5322276 0.77
SCHEMBL261271 0.77
SCHEMBL1636169 0.75
SCHEMBL1005273 0.75
SCHEMBL1686040 0.75
SCHEMBL225710 0.75
SCHEMBL7955186 0.71
SCHEMBL5661333 0.71
SCHEMBL21550073 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3615527-B1 NEW AZAQUINOLINE DERIVATIVES ELANCO ANIMAL HEALTH GMBH (DE) 2024-03-06 EP disclosed
CN-110770227-B Novel azaquinoline derivatives 拜耳动物保健有限责任公司 2024-03-01 CN disclosed
US-20230174492-A1 SUBSTITUTED CONDENSED AZINES AS ANTHELMINTIC COMPOUNDS ELANCO ANIMAL HEALTH GMBH (DE) 2023-06-08 US disclosed
CN-110536892-B Novel bicyclic pyrazole derivatives 拜耳动物保健有限责任公司 2023-05-12 CN disclosed
EP-4132911-A1 SUBSTITUTED CONDENSED AZINES AS ANTHELMINTIC COMPOUNDS Bayer Animal Health GmbH (DE) 2023-02-15 EP disclosed
CN-115667221-A Substituted fused oxazines as insect repellent compounds 拜耳动物保健有限责任公司 2023-01-31 CN disclosed
CN-115485266-A Benzimidazole derivatives 豪夫迈·罗氏有限公司 2022-12-16 CN disclosed
CN-115397812-A Indazole derivatives 豪夫迈·罗氏有限公司 2022-11-25 CN disclosed
US-11485733-B2 Azaquinoline derivatives BAYER ANIMAL HEALTH GMBH (DE) 2022-11-01 US disclosed
US-11130768-B2 Bicyclic pyrazole derivatives BAYER ANIMAL HEALTH GMBH (DE) 2021-09-28 US disclosed
EP-1781652-A1 PYRROLOPYRIMIDINE AND PYRROLOPYRIDINE DERIVATIVES SUBSTITUTED WITH TETRAHYDROPYRIDINE AS CRF ANTAGONISTS TAISHO PHARMACEUTICAL CO., LTD (JP) 2007-05-09 EP disclosed
EP-1758903-A1 PYRROLOPYRAMIDINE AND PYRROLOPYRIDINE DERIVATIVES SUBSTITUTED WITH A CYCLIC AMINO GROUP AS CRF ANTAGONISTS TAISHO PHARMACEUTICAL CO., LTD (JP) 2007-03-07 EP disclosed
WO-2006001511-A1 PYRROLOPYRIMIDINE AND PYRROLOPYRIDINE DERIVATIVES SUBSTITUTED WITH A CYCLIC AMINO GROUP AS CRF ANTAGONISTS TAISHO PHARMACEUTICAL CO., LTD. (JP) 2006-01-05 WO disclosed
WO-2006001501-A1 PYRROLOPYRIMIDINE AND PYRROLOPYRIDINE DERIVATIVES SUBSTITUTED WITH TETRAHYDROPYRIDINE AS CRF ANTAGONISTS TAISHO PHARMACEUTICAL CO., LTD. (JP) 2006-01-05 WO disclosed
CN-1692115-A Pyrrolopyrimidine and pyrrolopyridine derivatives substituted with cyclic amino group TAISHO PHARMACEUTICAL CO LTD (JP) 2005-11-02 CN disclosed
US-20050209253-A1 Pyrrolopyrimidine and pyrrolopyridine derivatives substituted with cyclic amino group TAISHO PHARMACEUTICAL CO., LTD. (JP) 2005-09-22 US disclosed
EP-1467997-A1 PYRROLOPYRIMIDINE AND PYRROLOPYRIDINE DERIVATIVES SUBSTITUTED WITH CYCLIC AMINO GROUP Taisho Pharmaceutical Co. Ltd. (JP) 2004-10-20 EP disclosed
WO-2004058767-A1 PYRROLOPYRIMIDINE AND PYRROLOPYRIDINE DERIVATIVES SUBSTITUTED WITH CYCLIC AMINO GROUP TAISHO PHARMACEUTICAL CO., LTD. (JP) 2004-07-15 WO disclosed
WO-2001092236-A1 4-ALKYL HALIDE TRIAZINE COMPOUNDS USED AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 2001-12-06 WO disclosed
WO-2001090085-A2 6-METHYL-4-TRIHALOMETHYLTRIAZINE COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2001-11-29 WO disclosed