Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 10/20 | 0.55 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 12/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.46 |
| ▸ | CASP1 | P29466 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16379209 | 0.89 | MAPT (0.59) | ADORA1IDO1APPMAPTALDH1A1 | |
| SCHEMBL14659978 | 0.88 | ADORA1 (0.68) | ADORA1IDO1APPMAPTALDH1A1 | |
| SCHEMBL16379210 | 0.85 | MAPT (0.48) | ADORA1IDO1APPMAPTALDH1A1 | |
| SCHEMBL16379178 | 0.85 | MAPT (0.48) | ADORA1IDO1APPMAPTALDH1A1 | |
| SCHEMBL16379141 | 0.84 | MAPT (0.45) | ADORA1IDO1APPMAPTALDH1A1 | |
| SCHEMBL16379173 | 0.84 | MAPT (0.45) | ADORA1IDO1APPMAPTALDH1A1 | |
| SCHEMBL16379192 | 0.84 | MAPT (0.59) | ADORA1IDO1APPMAPTALDH1A1 | |
| SCHEMBL16379171 | 0.83 | MAPT (0.44) | ADORA1IDO1APPMAPTALDH1A1 | |
| SCHEMBL16379113 | 0.83 | MAPT (0.44) | ADORA1IDO1APPMAPTALDH1A1 | |
| SCHEMBL16379149 | 0.82 | MAPT (0.43) | ADORA1IDO1APPMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150004100-A1 | HETEROCYCLIC COMPOUNDS AS IMAGING PROBES OF TAU PATHOLOGY | GE HEALTHCARE LIMITED (GB) | 2015-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150004100-A1 | HETEROCYCLIC COMPOUNDS AS IMAGING PROBES OF TAU PATHOLOGY | MAPT, NAT1, APP | ADORA1 438/4885IDO1 611/4885APP 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.