SCHEMBL16381376

SCHEMBL16381376

CCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)OCCNC(=O)C(N)Cc1cnc[nH]1)OC(=O)CCCCCCCCCCCCC

nearest known ligand 0.51

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ FABP3 P05413 1/20 0.51
▸ TLR2 O60603 14/20 0.50
▸ LPAR3 Q9UBY5 4/20 0.49
▸ LPAR1 Q92633 3/20 0.49
▸ ENPP2 Q13822 1/20 0.47
▸ SMN1; SMN2 Q16637 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16381380 1.00 FABP3 (0.51) FABP3TLR2LPAR3LPAR1ENPP2
SCHEMBL16381377 1.00 FABP3 (0.51) FABP3TLR2LPAR3LPAR1ENPP2
SCHEMBL16381549 0.96 SELP (0.53) FABP3TLR2
SCHEMBL16381378 0.96 SELP (0.53) FABP3TLR2
SCHEMBL16381381 0.94 SELP (0.55) FABP3TLR2
SCHEMBL16381548 0.89 SELP (0.51) FABP3TLR2
SCHEMBL16381545 0.89 SELP (0.51) FABP3TLR2
SCHEMBL10060216 0.85 TLR2 (0.48) TLR2
SCHEMBL16381379 0.84 TLR2 (0.47) TLR2LPAR3LPAR1
SCHEMBL10600918 0.81 FABP3 (0.65) FABP3TLR2LPAR3LPAR1ENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9540638-B2 Lipid particle, nucleic acid transfer carrier, compound for manufacturing nucleic acid transfer carrier, method for manufacturing lipid particle, and gene transfer method FUJIFILM CORPORATION (JP) 2017-01-10 — — US disclosed
US-20150004695-A1 LIPID PARTICLE, NUCLEIC ACID TRANSFER CARRIER, COMPOUND FOR MANUFACTURING NUCLEIC ACID TRANSFER CARRIER, METHOD FOR MANUFACTURING LIPID PARTICLE, AND GENE TRANSFER METHOD FUJIFILM CORPORATION (JP) 2015-01-01 — — US disclosed
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