Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | STS | P08842 | 3/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL962193 | 1.00 | USP2 (0.56) | USP2MAPTMAPK1KDM4EALDH1A1 | |
| SCHEMBL962194 | 1.00 | USP2 (0.56) | USP2MAPTMAPK1KDM4EALDH1A1 | |
| SCHEMBL217619 | 0.95 | USP2 (0.55) | USP2MAPTMAPK1KDM4EALDH1A1 | |
| SCHEMBL217620 | 0.95 | USP2 (0.55) | USP2MAPTMAPK1KDM4EALDH1A1 | |
| SCHEMBL962403 | 0.93 | MAPT (0.54) | USP2MAPTMAPK1KDM4EALDH1A1 | |
| SCHEMBL962405 | 0.93 | MAPT (0.54) | USP2MAPTMAPK1KDM4EALDH1A1 | |
| SCHEMBL220244 | 0.91 | USP2 (0.58) | USP2MAPTMAPK1KDM4EALDH1A1 | |
| SCHEMBL220243 | 0.91 | USP2 (0.58) | USP2MAPTMAPK1KDM4EALDH1A1 | |
| SCHEMBL217880 | 0.90 | USP2 (0.56) | USP2MAPTMAPK1KDM4EALDH1A1 | |
| SCHEMBL2738503 | 0.90 | USP2 (0.56) | USP2MAPTMAPK1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014207311-A1 | THERAPEUTICALLY ACTIVE ESTRATRIENTHIAZOLE DERIVATIVES AS INHIBITORS OF 17.BETA.-HYDROXY-STEROID DEHYDROGENASE, TYPE 1 | FORENDO PHARMA LTD (FI) | 2014-12-31 | — | — | WO | disclosed |