Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.52 |
| ▸ | RXRB | P28702 | 1/20 | 0.52 |
| ▸ | RXRG | P48443 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.45 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18831634 | 0.85 | MRGPRX4 (0.53) | APEX1MRGPRX4FOLH1CLCN2 | |
| SCHEMBL16920918 | 0.85 | MRGPRX4 (0.56) | TP53MRGPRX4 | |
| SCHEMBL16920923 | 0.85 | MRGPRX4 (0.49) | APEX1ALDH1A1HTTTP53MRGPRX4 | |
| SCHEMBL5291219 | 0.84 | HTT (0.68) | RXRARXRBRXRGAPEX1ALDH1A1 | |
| SCHEMBL16223754 | 0.83 | SLC22A12 (0.50) | RXRARXRBRXRGAPEX1ALDH1A1 | |
| SCHEMBL17788229 | 0.82 | MRGPRX4 (0.55) | APEX1HTTTP53MRGPRX4PTGDR2 | |
| SCHEMBL16385319 | 0.82 | MRGPRX4 (0.55) | RXRARXRBRXRGAPEX1ALDH1A1 | |
| SCHEMBL18831439 | 0.82 | MRGPRX4 (0.47) | APEX1ALDH1A1HTTTP53MRGPRX4 | |
| SCHEMBL17788226 | 0.81 | MRGPRX4 (0.51) | RXRARXRBRXRGAPEX1ALDH1A1 | |
| SCHEMBL23506122 | 0.79 | MRGPRX4 (0.47) | RXRARXRBRXRGALDH1A1MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015005499-A1 | TETRAZOLINONE COMPOUND AND USE THEREOF | 住友化学株式会社 (JP) | 2015-01-15 | — | — | WO | disclosed |