Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 20/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 20/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL501002 | 0.97 | HSP90AA1 (0.47) | HSP90AA1HSP90AB1 | |
| SCHEMBL16385335 | 0.95 | HSP90AA1 (0.45) | HSP90AA1HSP90AB1 | |
| SCHEMBL3412021 | 0.92 | HSP90AA1 (0.46) | HSP90AA1HSP90AB1 | |
| Benzyl Alcohol SCHEMBL16385336 | 0.91 | HSP90AA1 (0.45) | HSP90AA1HSP90AB1 | |
| SCHEMBL501682 | 0.88 | HSP90AA1 (0.48) | HSP90AA1HSP90AB1 | |
| SCHEMBL1148585 | 0.86 | HSP90AA1 (0.58) | HSP90AA1HSP90AB1 | |
| SCHEMBL16385337 | 0.86 | HSP90AA1 (0.46) | HSP90AA1HSP90AB1 | |
| SCHEMBL3469598 | 0.84 | HSP90AA1 (0.42) | HSP90AA1HSP90AB1 | |
| SCHEMBL3412023 | 0.82 | HSP90AA1 (0.47) | HSP90AA1HSP90AB1 | |
| SCHEMBL1304453 | 0.82 | HSP90AB1 (0.49) | HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9539243-B2 | Triazole compounds that modulate HSP90 activity | SYNTA PHARMACEUTICALS CORP. (US) | 2017-01-10 | — | — | US | disclosed |
| US-8937094-B2 | Triazole compounds that modulate HSP90 activity | SYNTA PHARMACEUTICALS CORP. (US) | 2015-01-20 | — | — | US | disclosed |