SCHEMBL16385754

SCHEMBL16385754

CCOc1ccc(C2CCC(C3CCC4CCC4C3)CC2)c(F)c1F

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 2/20 0.38
SCN9A Q15858 4/20 0.33
HTR2C P28335 3/20 0.33
HTR2B P41595 3/20 0.33
HTR2A P28223 2/20 0.33
FPR2 P25090 2/20 0.31
L3MBTL1 Q9Y468 2/20 0.31
HCRTR2 O43614 1/20 0.31
ALDH1A1 P00352 2/20 0.31
TSPO P30536 1/20 0.31
MRGPRX1 Q96LB2 1/20 0.31
CYP1A2 P05177 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C19 P33261 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
HTR1A P08908 1/20 0.30
SLC6A2 P23975 1/20 0.30
SLC6A4 P31645 1/20 0.30
LMNA P02545 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17827785 0.95 KDM1A (0.38) KDM1AHTR2CHTR2BHTR2AFPR2
SCHEMBL26209540 0.95 KDM1A (0.38) KDM1AHTR2CHTR2BHTR2AFPR2
SCHEMBL26209563 0.95 KDM1A (0.38) KDM1AHTR2CHTR2BHTR2AFPR2
SCHEMBL17827780 0.95 KDM1A (0.38) KDM1AHTR2CHTR2BHTR2AFPR2
SCHEMBL16768993 0.91 KDM1A (0.35) KDM1AHTR2AALDH1A1CYP1A2CYP2C19
SCHEMBL25929345 0.91 CAMKK1 (0.36) KDM1AHTR2AALDH1A1LMNAHPGD
SCHEMBL26209548 0.91 CAMKK1 (0.36) KDM1AHTR2AALDH1A1LMNAHPGD
SCHEMBL25929309 0.91 KDM1A (0.35) KDM1AHTR2AALDH1A1CYP1A2CYP2C19
SCHEMBL16768995 0.91 CAMKK1 (0.36) KDM1AHTR2AALDH1A1LMNAHPGD
SCHEMBL14922531 0.91 KDM1A (0.41) KDM1AHTR2CHTR2BHTR2AFPR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2824161-A1 LIQUID-CRYSTAL COMPOSITION AND LIQUID-CRYSTAL DISPLAY ELEMENT OBTAINED USING SAME DIC Corporation (JP) 2015-01-14 EP disclosed