⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18885187 | 0.64 | CRBN (0.30) | — | |
| SCHEMBL907942 | 0.63 | — | — | |
| SCHEMBL11223089 | 0.61 | — | — | |
| Hydrochloric Acid SCHEMBL4412668 | 0.61 | — | — | |
| SCHEMBL19723096 | 0.60 | — | — | |
| SCHEMBL10205055 | 0.58 | — | — | |
| SCHEMBL4630094 | 0.57 | — | — | |
| Hydrochloric Acid SCHEMBL4013495 | 0.56 | — | — | |
| SCHEMBL9574785 | 0.56 | — | — | |
| SCHEMBL11194126 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024138201-A2 | SELECTIVE BET INHIBITORS AND USES THEREOF | Tay Therapeutics Limited (GB) | 2024-06-27 | — | — | WO | disclosed |
| EP-3877376-B1 | PYRIDAZINONE COMPOUNDS AND USES THEREOF | EDGEWISE THERAPEUTICS INC (US) | 2023-08-23 | — | — | EP | disclosed |
| WO-2023275542-A1 | PYRROLOPYRIDONE DERIVATIVES USEFUL IN THE TREATMENT OF CANCER | Tay Therapeutics Limited (GB) | 2023-01-05 | — | — | WO | disclosed |
| WO-2020150677-A1 | HETEROCYCLIC COMPOUNDS AS ADENOSINE ANTAGONISTS | NUVATION BIO INC. (US) | 2020-07-23 | — | — | WO | disclosed |
| CN-106255688-B | Morpholine-pyridine derivate | 豪夫迈·罗氏有限公司 | 2019-11-08 | — | — | CN | disclosed |
| US-8921378-B2 | Androgen receptor modulating carboxamides | ORION CORPORATION (FI) | 2014-12-30 | — | — | US | disclosed |