Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL363040 | 0.85 | BACE1 (1.00) | BACE1APP | |
| SCHEMBL16390617 | 0.80 | BACE1 (0.75) | BACE1APP | |
| SCHEMBL16390857 | 0.80 | BACE1 (0.71) | BACE1APP | |
| SCHEMBL16390745 | 0.80 | BACE1 (0.73) | BACE1APP | |
| SCHEMBL16390758 | 0.80 | BACE1 (0.73) | BACE1APP | |
| SCHEMBL16390615 | 0.78 | BACE1 (0.75) | BACE1APP | |
| SCHEMBL16390726 | 0.78 | BACE1 (0.74) | BACE1APP | |
| SCHEMBL16390849 | 0.78 | BACE1 (0.74) | BACE1APP | |
| SCHEMBL16390707 | 0.77 | BACE1 (0.73) | BACE1APP | |
| SCHEMBL16390882 | 0.77 | BACE1 (0.59) | BACE1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2456763-B1 | OXAZINE DERIVATIVES AND THEIR USE AS BACE INHIBITORS FOR THE TREATMENT OF NEUROLOGICAL DISORDERS | NOVARTIS AG (CH) | 2015-01-21 | — | — | EP | claimed |