Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 4/20 | 0.65 |
| ▸ | SCN10A | Q9Y5Y9 | 4/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16408281 | 0.90 | — | — | |
| SCHEMBL16398236 | 0.83 | SCN8A (0.58) | SCN8ASCN10A | |
| SCHEMBL16408275 | 0.82 | — | — | |
| SCHEMBL16398130 | 0.78 | — | — | |
| SCHEMBL15901781 | 0.78 | SCN8A (1.00) | SCN8ASCN10A | |
| SCHEMBL30535900 | 0.78 | — | — | |
| SCHEMBL16408277 | 0.78 | — | — | |
| SCHEMBL16408304 | 0.78 | — | — | |
| SCHEMBL16408303 | 0.78 | — | — | |
| SCHEMBL17791071 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3022175-A1 | SULFONAMIDES AS MODULATORS OF SODIUM CHANNELS | Vertex Pharmaceuticals Inc. (US) | 2016-05-25 | — | — | EP | disclosed |
| WO-2015010065-A1 | SULFONAMIDES AS MODULATORS OF SODIUM CHANNELS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2015-01-22 | — | — | WO | disclosed |