Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.40 |
| ▸ | HBB | P68871 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 2/20 | 0.40 |
| ▸ | HTR1B | P28222 | 2/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16398479 | 1.00 | HTR2A (0.47) | HTR2AHTR2CHTR2BALDH1A1KDM4E | |
| SCHEMBL16398448 | 0.81 | HTR2C (0.53) | HTR2AHTR2CHTR2BALDH1A1KDM4E | |
| SCHEMBL17747344 | 0.81 | HTR2C (0.53) | HTR2AHTR2CHTR2BALDH1A1KDM4E | |
| SCHEMBL12129219 | 0.76 | HTR1D (0.61) | HTR2AHTR2CHTR2BALDH1A1KDM4E | |
| SCHEMBL195657 | 0.75 | PTGDR2 (0.62) | HTR2AHTR2CHTR2BALDH1A1KDM4E | |
| SCHEMBL5669748 | 0.72 | SLC6A2 (0.68) | HTR2CHTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL18312709 | 0.72 | HTR2C (0.50) | HTR2AHTR2CHTR2BALDH1A1KDM4E | |
| SCHEMBL1050248 | 0.72 | HTR2C (0.50) | HTR2AHTR2CHTR2BALDH1A1KDM4E | |
| SCHEMBL16398264 | 0.72 | HTR2C (0.44) | HTR2AHTR2CHTR2BSLC6A2SLC6A4 | |
| SCHEMBL16398268 | 0.72 | HTR2C (0.44) | HTR2AHTR2CHTR2BSLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3004120-A1 | SPIRO-1,1'-BIINDANE-7,7-BISPHOSPHINE OXIDES AS HIGHLY ACTIVE SUPPORTING LIGANDS FOR PALLADIUM-CATALYZED ASYMMETRIC HECK REACTION | Nanyang Technological University (SG) | 2016-04-13 | — | — | EP | disclosed |
| WO-2014196930-A1 | SPIRO-1,1'-BIINDANE-7,7-BISPHOSPHINE OXIDES AS HIGHLY ACTIVE SUPPORTING LIGANDS FOR PALLADIUM-CATALYZED ASYMMETRIC HECK REACTION | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2014-12-11 | — | — | WO | disclosed |