Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | BLM | P54132 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | GMNN | O75496 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | APEX1 | P27695 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | F7 | P08709 | 2/20 | 0.44 |
| ▸ | F3 | P13726 | 2/20 | 0.44 |
| ▸ | TERT | O14746 | 3/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | FABP4 | P15090 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16401332 | 1.00 | CYP2C19 (0.49) | CYP2C19CYP1A2BLMHSD17B10GMNN | |
| SCHEMBL16401654 | 1.00 | CYP2C19 (0.49) | CYP2C19CYP1A2BLMHSD17B10GMNN | |
| SCHEMBL20680343 | 0.94 | CYP1A2 (0.56) | CYP2C19CYP1A2BLMHSD17B10GMNN | |
| SCHEMBL19357333 | 0.94 | CYP1A2 (0.56) | CYP2C19CYP1A2BLMHSD17B10GMNN | |
| SCHEMBL14322640 | 0.93 | CYP1A2 (0.58) | CYP2C19CYP1A2BLMHSD17B10GMNN | |
| SCHEMBL600897 | 0.93 | CYP1A2 (0.58) | CYP2C19CYP1A2BLMHSD17B10GMNN | |
| SCHEMBL600896 | 0.93 | CYP1A2 (0.58) | CYP2C19CYP1A2BLMHSD17B10GMNN | |
| SCHEMBL23534464 | 0.88 | CYP2C19 (0.43) | CYP2C19CYP1A2BLMHSD17B10GMNN | |
| SCHEMBL366777 | 0.88 | CYP2C19 (0.43) | CYP2C19CYP1A2BLMHSD17B10GMNN | |
| SCHEMBL599741 | 0.88 | CYP2C19 (0.43) | CYP2C19CYP1A2BLMHSD17B10GMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3280431-B1 | DISRUPTION OF THE WAVE3 PROTEIN COMPLEX FOR SUPPRESSION OF INVASION AND METASTASIS | UNIV GEORGIA (US) | 2023-11-08 | — | — | EP | disclosed |
| US-11773146-B2 | Disruption of the WAVE3 protein complex for suppression of invasion and metastasis | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2023-10-03 | — | — | US | disclosed |
| US-20230220019-A1 | CHEMICALLY-STABILIZED ALLOSTERIC MODULATORS OF LEUCINERICH REPEAT KINASE 2 (LRRK2) | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | 2023-07-13 | — | — | US | disclosed |
| US-20210024595-A1 | DISRUPTION OF THE WAVE3 PROTEIN COMPLEX FOR SUPPRESSION OF INVASION AND METASTASIS | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | 2021-01-28 | — | — | US | disclosed |
| US-10822380-B2 | Disruption of the WAVE3 protein complex for suppression of invasion and metastasis | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2020-11-03 | — | — | US | disclosed |
| US-20180072782-A1 | DISRUPTION OF THE WAVE3 PROTEIN COMPLEX FOR SUPPRESSION OF INVASION AND METASTASIS | AUGUSTA UNIVERSITY RESEARCH INSTITUTE, INC. | 2018-03-15 | — | — | US | disclosed |
| EP-3280431-A1 | DISRUPTION OF THE WAVE3 PROTEIN COMPLEX FOR SUPPRESSION OF INVASION AND METASTASIS | University of Georgia Research Foundation Inc. (US) | 2018-02-14 | — | — | EP | disclosed |
| WO-2016164768-A1 | DISRUPTION OF THE WAVE3 PROTEIN COMPLEX FOR SUPPRESSION OF INVASION AND METASTASIS | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2016-10-13 | — | — | WO | disclosed |
| WO-2015010048-A1 | CHEMICALLY-STABILIZED A KINASE ANCHORING PROTEIN (AKAP) PEPTIDE DISRUPTORS | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2015-01-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230220019-A1 | CHEMICALLY-STABILIZED ALLOSTERIC MODULATORS OF LEUCINERICH REPEAT KINASE 2 (LRRK2) | LRRK2, TLK2, LMTK2 | CYP2C19 4820/4885CYP1A2 4817/4885BLM 2096/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.