Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.68 |
| ▸ | LMNA | P02545 | 4/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | ESR1 | P03372 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.54 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Hydroxybenzoic Acid Butyl Ester SCHEMBL29421150 | 0.98 | TSHR (0.80) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| 2-Hydroxybenzoic Acid Butyl Ester SCHEMBL62565 | 0.98 | TSHR (0.80) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| 2-Hydroxybenzoic Acid Butyl Ester SCHEMBL27838988 | 0.97 | TSHR (0.77) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| 2-Hydroxybenzoic Acid Butyl Ester SCHEMBL27413133 | 0.97 | TSHR (0.77) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| 2-Hydroxybenzoic Acid Butyl Ester SCHEMBL28316995 | 0.97 | TSHR (0.77) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| 2-Hydroxybenzoic Acid Butyl Ester SCHEMBL3362976 | 0.97 | TSHR (0.77) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| 2-Hydroxybenzoic Acid Butyl Ester SCHEMBL8013639 | 0.97 | TSHR (0.77) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| 2-Hydroxybenzoic Acid Butyl Ester SCHEMBL5526965 | 0.97 | TSHR (0.77) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| 2-Hydroxybenzoic Acid Butyl Ester SCHEMBL29613017 | 0.97 | TSHR (0.77) | TSHRTDP1L3MBTL1MAPK1CYP3A4 | |
| 2-Hydroxybenzoic Acid Butyl Ester SCHEMBL27433946 | 0.97 | TSHR (0.77) | TSHRTDP1L3MBTL1MAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116807955-A | Tooth-strengthening gum-strengthening toothpaste and preparation method thereof | 上海市口腔医院(上海市口腔健康中心) | 2023-09-29 | — | — | CN | claimed |
| CN-112137940-B | Compound sugarcane leaf toothpaste and preparation method thereof | 广西中医药大学 | 2022-11-15 | — | — | CN | claimed |
| CN-108272862-B | Pudilan oral spray and preparation method thereof | 济川药业集团有限公司 | 2021-01-05 | — | — | CN | claimed |
| CN-112137940-A | Compound sugarcane leaf toothpaste and preparation method thereof | 广西中医药大学 | 2020-12-29 | — | — | CN | claimed |
| CN-108379139-B | Toothpaste for preventing and treating dental ulcer and preparation method and application thereof | 济川药业集团有限公司 | 2020-12-08 | — | — | CN | claimed |
| CN-108379139-A | A kind of toothpaste and its preparation method and application of anti-treating dental ulcer | 济川药业集团有限公司 | 2018-08-10 | — | — | CN | claimed |
| CN-108272862-A | A kind of Pudilan oral spray and preparation method thereof | 济川药业集团有限公司 | 2018-07-13 | — | — | CN | claimed |
| CN-107753390-A | A kind of anti-inflammation toothpaste and preparation method thereof | 青岛海芬健康产业科技有限公司 | 2018-03-06 | — | — | CN | claimed |
| US-9682021-B2 | Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses | FOAMIX PHARMACEUTICALS LTD. (IL) | 2017-06-20 | — | — | US | claimed |
| CN-104224923-A | Tea tree essential oil antimicrobial gel for treating vaginal disease in gynecology | HAINAN HOTMED TIANYA PHARMACEUTICAL CO LTD | 2014-12-24 | — | — | CN | claimed |
| US-20140248219-A1 | SUBSTANTIALLY NON-AQUEOUS FOAMABLE PETROLATUM BASED PHARMACEUTICAL AND COSMETIC COMPOSITIONS AND THEIR USES | FOAMIX LTD. (IL) | 2014-09-04 | — | — | US | claimed |
| US-8795635-B2 | Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses | FOAMIX LTD. (IL) | 2014-08-05 | — | — | US | claimed |
| EP-2257276-A2 | SUBSTANTIALLY NON-AQUEOUS FOAMABLE PETROLATUM BASED PHARMACEUTICAL AND COSMETIC COMPOSITIONS AND THEIR USES | Foamix Ltd. (IL) | 2010-12-08 | — | — | EP | claimed |
| US-20100221195-A1 | SUBSTANTIALLY NON-AQUEOUS FOAMABLE PETROLATUM BASED PHARMACEUTICAL AND COSMETIC COMPOSITIONS AND THEIR USES | FOAMIX LTD. (IL) | 2010-09-02 | — | — | US | claimed |
| WO-2009098595-A2 | SUBSTANTIALLY NON-AQUEOUS FOAMABLE PETROLATUM BASED PHARMACEUTICAL AND COSMETIC COMPOSITIONS AND THEIR USES | FOAMIX LTD. (IL) | 2009-08-13 | — | — | WO | claimed |
| EP-2073794-A2 | STABLE NON-ALCOHOLIC FOAMABLE PHARMACEUTICAL EMULSION COMPOSITIONS WITH AN UNCTUOUS EMOLLIENT AND THEIR USES | Foamix Ltd. (IL) | 2009-07-01 | — | — | EP | claimed |
| WO-2009007785-A2 | STABLE NON-ALCOHOLIC FOAMABLE PHARMACEUTICAL EMULSION COMPOSITIONS WITH AN UNCTUOUS EMOLLIENT AND THEIR USES | FOAMIX LTD. (US) | 2009-01-15 | — | — | WO | claimed |
| US-20080260655-A1 | stable, non-alcoholic, non-silicone, foamable carrier compositions comprising petrolatum, foam agent, propellant, | FOAMIX PHARMACEUTICALS LTD. (IL) | 2008-10-23 | — | — | US | claimed |
| US-20080206155-A1 | STABLE NON-ALCOHOLIC FOAMABLE PHARMACEUTICAL EMULSION COMPOSITIONS WITH AN UNCTUOUS EMOLLIENT AND THEIR USES | FOAMIX LTD. | 2008-08-28 | — | — | US | claimed |
| CN-116807955-A | Tooth-strengthening gum-strengthening toothpaste and preparation method thereof | 上海市口腔医院(上海市口腔健康中心) | 2023-09-29 | — | — | CN | disclosed |
| CN-112137940-B | Compound sugarcane leaf toothpaste and preparation method thereof | 广西中医药大学 | 2022-11-15 | — | — | CN | disclosed |
| CN-112603876-B | Ginger salt fire-clearing fresh toothpaste | 两面针（江苏）实业有限公司 | 2022-04-26 | — | — | CN | disclosed |
| CN-112603876-A | Ginger salt fire-clearing fresh toothpaste | 两面针（江苏）实业有限公司 | 2021-04-06 | — | — | CN | disclosed |
| CN-108272862-B | Pudilan oral spray and preparation method thereof | 济川药业集团有限公司 | 2021-01-05 | — | — | CN | disclosed |
| CN-112137940-A | Compound sugarcane leaf toothpaste and preparation method thereof | 广西中医药大学 | 2020-12-29 | — | — | CN | disclosed |
| CN-108379139-B | Toothpaste for preventing and treating dental ulcer and preparation method and application thereof | 济川药业集团有限公司 | 2020-12-08 | — | — | CN | disclosed |
| CN-108939097-A | One kind taking orally stomach-ultrasonography developer formuia and preparation method with liquid-type | 中国医科大学附属盛京医院 | 2018-12-07 | — | — | CN | disclosed |
| CN-108379139-A | A kind of toothpaste and its preparation method and application of anti-treating dental ulcer | 济川药业集团有限公司 | 2018-08-10 | — | — | CN | disclosed |
| CN-108272862-A | A kind of Pudilan oral spray and preparation method thereof | 济川药业集团有限公司 | 2018-07-13 | — | — | CN | disclosed |
| US-9682021-B2 | Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses | FOAMIX PHARMACEUTICALS LTD. (IL) | 2017-06-20 | — | — | US | disclosed |
| CN-104487047-A | Use of cyclohexanol ethers having antimicrobial properties | MERCK PATENT GMBH | 2015-04-01 | — | — | CN | disclosed |
| CN-104271109-A | Use of dicyclohexylmethanol derivatives with antimicrobial properties | MERCK PATENT GMBH | 2015-01-07 | — | — | CN | disclosed |
| CN-104224923-A | Tea tree essential oil antimicrobial gel for treating vaginal disease in gynecology | HAINAN HOTMED TIANYA PHARMACEUTICAL CO LTD | 2014-12-24 | — | — | CN | disclosed |
| US-20140248219-A1 | SUBSTANTIALLY NON-AQUEOUS FOAMABLE PETROLATUM BASED PHARMACEUTICAL AND COSMETIC COMPOSITIONS AND THEIR USES | FOAMIX LTD. (IL) | 2014-09-04 | — | — | US | disclosed |
| US-8795635-B2 | Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses | FOAMIX LTD. (IL) | 2014-08-05 | — | — | US | disclosed |
| CN-102186460-B | Pharmaceutical topical compositions | FERRER INT | 2013-06-12 | — | — | CN | disclosed |
| CN-102186460-A | Pharmaceutical topical compositions | FERRER INT | 2011-09-14 | — | — | CN | disclosed |
| US-20110097279-A1 | STABLE NON-ALCOHOLIC FOAMABLE PHARMACEUTICAL EMULSION COMPOSITIONS WITH AN UNCTUOUS EMOLLIENT AND THEIR USES | FOAMIX LTD. (IL) | 2011-04-28 | — | — | US | disclosed |
| EP-2257276-A2 | SUBSTANTIALLY NON-AQUEOUS FOAMABLE PETROLATUM BASED PHARMACEUTICAL AND COSMETIC COMPOSITIONS AND THEIR USES | Foamix Ltd. (IL) | 2010-12-08 | — | — | EP | disclosed |
| US-20100221195-A1 | SUBSTANTIALLY NON-AQUEOUS FOAMABLE PETROLATUM BASED PHARMACEUTICAL AND COSMETIC COMPOSITIONS AND THEIR USES | FOAMIX LTD. (IL) | 2010-09-02 | — | — | US | disclosed |
| EP-2217251-A1 | METHODS OF AUGMENTING OR REPAIRING SOFT TISSUE | Genzyme Corporation (US) | 2010-08-18 | — | — | EP | disclosed |
| WO-2009098595-A2 | SUBSTANTIALLY NON-AQUEOUS FOAMABLE PETROLATUM BASED PHARMACEUTICAL AND COSMETIC COMPOSITIONS AND THEIR USES | FOAMIX LTD. (IL) | 2009-08-13 | — | — | WO | disclosed |
| EP-2073794-A2 | STABLE NON-ALCOHOLIC FOAMABLE PHARMACEUTICAL EMULSION COMPOSITIONS WITH AN UNCTUOUS EMOLLIENT AND THEIR USES | Foamix Ltd. (IL) | 2009-07-01 | — | — | EP | disclosed |
| WO-2009059121-A1 | METHODS OF AUGMENTING OR REPAIRING SOFT TISSUE | GENZYME CORPORATION (US) | 2009-05-07 | — | — | WO | disclosed |
| US-20090117188-A1 | Methods of Augmenting or Repairing Soft Tissue | GENZYME CORPORATION | 2009-05-07 | — | — | US | disclosed |
| WO-2009007785-A2 | STABLE NON-ALCOHOLIC FOAMABLE PHARMACEUTICAL EMULSION COMPOSITIONS WITH AN UNCTUOUS EMOLLIENT AND THEIR USES | FOAMIX LTD. (US) | 2009-01-15 | — | — | WO | disclosed |
| US-20080260655-A1 | stable, non-alcoholic, non-silicone, foamable carrier compositions comprising petrolatum, foam agent, propellant, | FOAMIX PHARMACEUTICALS LTD. (IL) | 2008-10-23 | — | — | US | disclosed |
| US-20080254124-A1 | Controlled release composition | BM RESEARCH A/S | 2008-10-16 | — | — | US | disclosed |
| US-20080206155-A1 | STABLE NON-ALCOHOLIC FOAMABLE PHARMACEUTICAL EMULSION COMPOSITIONS WITH AN UNCTUOUS EMOLLIENT AND THEIR USES | FOAMIX LTD. | 2008-08-28 | — | — | US | disclosed |
| US-20050019405-A1 | Controlled release composition | BM RESEARCH A/S | 2005-01-27 | — | — | US | disclosed |
| US-6787156-B1 | Controlled release composition | BM RESEARCH A/S (DK) | 2004-09-07 | — | — | US | disclosed |
| EP-0746310-B1 | CONTROLLED RELEASE COMPOSITION | BM RES AS (DK) | 1998-11-18 | — | — | EP | disclosed |
| EP-0746310-A1 | CONTROLLED RELEASE COMPOSITION | BUKH MEDITEC A/S (DK) | 1996-12-11 | — | — | EP | disclosed |
| WO-1995022962-A1 | CONTROLLED RELEASE COMPOSITION | BM RESEARCH A/S (DK) | 1995-08-31 | — | — | WO | disclosed |
| WO-1995022962-A1 | CONTROLLED RELEASE COMPOSITION | BM RESEARCH A/S (DK) | 1995-08-31 | — | — | WO | disclosed |