Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 8/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.74 |
| ▸ | MAOA | P21397 | 1/20 | 0.64 |
| ▸ | DDX3X | O00571 | 2/20 | 0.54 |
| ▸ | MIF | P14174 | 2/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | DRD4 | P21917 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | CD74 | P04233 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2821461 | 0.85 | NOTUM (1.00) | NOTUML3MBTL1MAOAKDM4EMAPT | |
| SCHEMBL17978468 | 0.83 | NOTUM (0.53) | NOTUML3MBTL1MAOADDX3XMIF | |
| SCHEMBL12601113 | 0.82 | NOTUM (0.64) | NOTUML3MBTL1MAOAMIFDRD2 | |
| SCHEMBL15057639 | 0.81 | NOTUM (0.63) | NOTUML3MBTL1MAOAMIFDRD2 | |
| SCHEMBL19564580 | 0.81 | NOTUM (0.54) | NOTUML3MBTL1MAOACA1CA2 | |
| Bromide SCHEMBL1894577 | 0.81 | NOTUM (0.62) | NOTUML3MBTL1MAOAMIFDRD2 | |
| SCHEMBL16284856 | 0.78 | NOTUM (0.58) | NOTUML3MBTL1MAOAMIFDRD2 | |
| SCHEMBL3777938 | 0.78 | NOTUM (0.68) | NOTUML3MBTL1MAOAMIFDRD2 | |
| SCHEMBL16401577 | 0.78 | NOTUM (1.00) | NOTUML3MBTL1MAOAMIFDRD2 | |
| SCHEMBL4434629 | 0.78 | NOTUM (0.68) | NOTUML3MBTL1MAOAMIFDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015007613-A1 | O-ALKYL TRIAZOLYL CARBAMATES AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE (FAAH) | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2015-01-22 | — | — | WO | disclosed |