Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 1.00 |
| ▸ | ERBB2 | P04626 | 20/20 | 1.00 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17821496 | 1.00 | EGFR (1.00) | EGFRERBB2ERBB4 | |
| SCHEMBL17821500 | 1.00 | EGFR (1.00) | EGFRERBB2ERBB4 | |
| SCHEMBL16403875 | 1.00 | EGFR (1.00) | EGFRERBB2ERBB4 | |
| SCHEMBL17821497 | 1.00 | EGFR (1.00) | EGFRERBB2ERBB4 | |
| SCHEMBL17821499 | 1.00 | EGFR (1.00) | EGFRERBB2ERBB4 | |
| SCHEMBL3578219 | 0.97 | EGFR (0.94) | EGFRERBB2ERBB4 | |
| SCHEMBL3581840 | 0.97 | EGFR (0.94) | EGFRERBB2ERBB4 | |
| SCHEMBL3578222 | 0.97 | EGFR (0.94) | EGFRERBB2ERBB4 | |
| SCHEMBL3581842 | 0.97 | EGFR (0.94) | EGFRERBB2ERBB4 | |
| SCHEMBL3578228 | 0.97 | EGFR (0.94) | EGFRERBB2ERBB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107892684-B | Quinazoline derivatives, pharmaceutical compositions thereof, and use as medicaments | 锦州奥鸿药业有限责任公司 | 2020-05-26 | — | — | CN | disclosed |
| EP-3022186-A1 | QUINAZOLINE DERIVATIVES, COMPOSITIONS THEREOF, AND USE AS PHARMACEUTICALS | Shanghai Fochon Pharmaceutical Co. Ltd (CN) | 2016-05-25 | — | — | EP | disclosed |
| WO-2015007219-A1 | QUINAZOLINE DERIVATIVES, COMPOSITIONS THEREOF, AND USE AS PHARMACEUTICALS | SHANGHAI FOCHON PHARMACEUTICAL CO LTD (CN) | 2015-01-22 | — | — | WO | disclosed |