Sugi Predict

Sugi Predict / Compounds / SCHEMBL16404244

SCHEMBL16404244

SCHEMBL16404244

Cc1nc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(Cl)n1-c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ CNR2 P34972 16/20 1.00
▸ CNR1 P21554 10/20 0.79
▸ FAAH O00519 1/20 0.50
▸ ALDH1A1 P00352 1/20 0.49
▸ HPGD P15428 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3687439 0.88 CNR2 (1.00) CNR2CNR1FAAHALDH1A1HPGD
SCHEMBL16404205 0.88 CNR2 (1.00) CNR2CNR1FAAH
SCHEMBL16404220 0.86 CNR2 (1.00) CNR2CNR1FAAHALDH1A1HPGD
SCHEMBL16404243 0.84 CNR2 (1.00) CNR2CNR1FAAHALDH1A1HPGD
SCHEMBL16404193 0.84 CNR2 (1.00) CNR2CNR1FAAHALDH1A1HPGD
SCHEMBL16404202 0.84 CNR2 (0.74) CNR2CNR1FAAHALDH1A1HPGD
SCHEMBL16404221 0.82 CNR2 (0.79) CNR2CNR1FAAHALDH1A1HPGD
SCHEMBL16404250 0.82 CNR2 (0.79) CNR2CNR1ALDH1A1HPGD
SCHEMBL16404259 0.81 CNR2 (1.00) CNR2CNR1ALDH1A1HPGD
SCHEMBL16404236 0.79 CNR2 (1.00) CNR2CNR1FAAHALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8937184-B2 1H-imidazole derivatives as cannabinoid CB2 receptor modulators ABBVIE B.V. (NL) 2015-01-20 — — US disclosed
US-8937184-B2 1H-imidazole derivatives as cannabinoid CB2 receptor modulators ABBVIE B.V. (NL) 2015-01-20 — — US disclosed