Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.56 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.55 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | MERTK | Q12866 | 4/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16404477 | 0.91 | PDE5A (0.66) | PDE5ANPY5RABCG2MEN1KMT2A | |
| SCHEMBL16404310 | 0.82 | NPY5R (0.73) | NPY5RABCG2MEN1KMT2AHTR2A | |
| SCHEMBL16404346 | 0.82 | NPY5R (0.59) | NPY5RABCG2MEN1KMT2AHTR2A | |
| SCHEMBL16404355 | 0.81 | ABCG2 (0.78) | PDE5ANPY5RABCG2MEN1KMT2A | |
| SCHEMBL4868370 | 0.81 | PDE5A (0.68) | PDE5ATP53ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL16404339 | 0.81 | ABCG2 (0.72) | PDE5ANPY5RABCG2MEN1KMT2A | |
| SCHEMBL16404331 | 0.79 | MEN1 (0.65) | NPY5RABCG2MEN1KMT2AHTR2A | |
| SCHEMBL16404332 | 0.76 | ABCG2 (0.69) | PDE5AABCG2MEN1KMT2ATP53 | |
| SCHEMBL4867367 | 0.76 | PDE5A (0.78) | PDE5ATP53ALDH1A1MAPK1SLC2A1 | |
| SCHEMBL16404337 | 0.75 | NPY5R (0.56) | NPY5RABCG2MEN1KMT2AMERTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8936840-B2 | Retardation film, polarizing plate, liquid crystal display device, and compound | Konica Minolta, Inc. (JP) | 2015-01-20 | — | — | US | disclosed |