SCHEMBL16405283

SCHEMBL16405283

c1ccc(-c2cc(-c3ccccc3)cc(-n3c4ccccc4c4cc(-c5ccc6c7ccccc7n(-c7cccc(-c8cc(-c9ccccc9)cc(-c9ccccc9)n8)c7)c6c5)ccc43)c2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.39
ATM Q13315 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
TSPO P30536 1/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
GAA P10253 2/20 0.34
PTGER4 P35408 1/20 0.33
PTGES O14684 1/20 0.33
PDE10A Q9Y233 1/20 0.33
GABRG2 P18507 1/20 0.33
GABRB3 P28472 1/20 0.33
GABRA5 P31644 1/20 0.33
GABRA3 P34903 1/20 0.33
CYP19A1 P11511 1/20 0.33
NPY5R Q15761 1/20 0.33
DHODH Q02127 1/20 0.33
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
TET2 Q6N021 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14748700 1.00 KDM4E (0.39) KDM4EATML3MBTL1TSPOMEN1
SCHEMBL14748678 0.99 KDM4E (0.40) KDM4EATML3MBTL1TSPOMEN1
SCHEMBL14748723 0.99 KDM4E (0.40) KDM4EATML3MBTL1TSPOMEN1
SCHEMBL14748698 0.98 KDM4E (0.41) KDM4EATML3MBTL1TSPOMEN1
SCHEMBL14748658 0.98 KDM4E (0.41) KDM4EATML3MBTL1TSPOMEN1
SCHEMBL6373994 0.96 KDM4E (0.43) KDM4EATML3MBTL1TSPOMEN1
SCHEMBL14748647 0.96 KDM4E (0.43) KDM4EATML3MBTL1TSPOMEN1
SCHEMBL14748741 0.96 KDM4E (0.41) KDM4EATML3MBTL1TSPOMEN1
SCHEMBL14748679 0.96 KDM4E (0.41) KDM4EATML3MBTL1TSPOMEN1
SCHEMBL14748613 0.96 KDM4E (0.41) KDM4EATML3MBTL1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2871223-A1 COMPOSITE FOR ORGANIC LIGHT-EMITTING DIODE, ORGANIC LIGHT-EMITTING LAYER INCLUDING SAME, AND ORGANIC LIGHT-EMITTING DIODE Samsung SDI Co., Ltd. (KR) 2015-05-13 EP disclosed
US-20150021585-A1 COMPOSITION FOR ORGANIC LIGHT-EMITTING DIODE, ORGANIC LIGHT-EMITTING LAYER INCLUDING SAME, AND ORGANIC LIGHT-EMITTING DIODE SAMSUNG SDI CO., LTD. (KR) 2015-01-22 US disclosed
US-20150021585-A1 COMPOSITION FOR ORGANIC LIGHT-EMITTING DIODE, ORGANIC LIGHT-EMITTING LAYER INCLUDING SAME, AND ORGANIC LIGHT-EMITTING DIODE SAMSUNG SDI CO., LTD. (KR) 2015-01-22 US disclosed