SCHEMBL16407301

SCHEMBL16407301

C=CC(=O)OCC(O)CN(CC)CCC

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.47
HPGD P15428 1/20 0.42
LMNA P02545 1/20 0.38
ABCB1 P08183 4/20 0.36
ALDH1A1 P00352 5/20 0.35
ABCB11 O95342 1/20 0.34
KCNH2 Q12809 1/20 0.34
TP53 P04637 3/20 0.34
HIF1A Q16665 3/20 0.34
CYP3A4 P08684 2/20 0.34
HSD17B10 Q99714 1/20 0.34
THRB P10828 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
HSF1 Q00613 1/20 0.33
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1254957 0.92 TSHR (0.52) TSHRHPGDLMNAABCB1ALDH1A1
Fluoride SCHEMBL1254178 0.90 TSHR (0.50) TSHRHPGDLMNAABCB1ALDH1A1
Iodide SCHEMBL1254370 0.90 TSHR (0.50) TSHRHPGDLMNAABCB1ALDH1A1
Hydrochloric Acid SCHEMBL1254946 0.90 TSHR (0.50) TSHRHPGDLMNAABCB1ALDH1A1
Bromide SCHEMBL1254987 0.90 TSHR (0.50) TSHRHPGDLMNAABCB1ALDH1A1
Acrylic Acid Methyl Ester SCHEMBL27684592 0.86 TSHR (0.46) TSHRHPGDLMNAABCB1ALDH1A1
Methacrylic Acid SCHEMBL27716379 0.84 TSHR (0.44) TSHRHPGDLMNAABCB1ALDH1A1
SCHEMBL1302161 0.81 TSHR (0.50) TSHRHPGDLMNAABCB1ALDH1A1
SCHEMBL10931967 0.81 TSHR (0.46) TSHRHPGDLMNAALDH1A1TP53
SCHEMBL1302837 0.79 TSHR (0.49) TSHRHPGDLMNAALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9175186-B2 Coating compositions having chelant functionality ROHM AND HAAS COMPANY 2015-11-03 US disclosed
US-20150051336-A1 COATING COMPOSITIONS HAVING CHELANT FUNCTIONALITY ROHM AND HAAS COMPANY 2015-02-19 US disclosed
US-20150025177-A1 COATING COMPOSITIONS HAVING CHELANT FUNCTIONALITY ROHM AND HAAS COMPANY 2015-01-22 US disclosed