Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 20/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16402587 | 0.95 | EZH2 (0.63) | EZH2 | |
| SCHEMBL16402585 | 0.95 | EZH2 (0.63) | EZH2 | |
| SCHEMBL16398464 | 0.89 | EZH2 (0.66) | EZH2 | |
| SCHEMBL16402502 | 0.89 | EZH2 (0.66) | EZH2 | |
| SCHEMBL16403078 | 0.88 | EZH2 (0.65) | EZH2 | |
| SCHEMBL16402519 | 0.88 | EZH2 (0.65) | EZH2 | |
| SCHEMBL16403076 | 0.88 | EZH2 (0.65) | EZH2 | |
| SCHEMBL17891335 | 0.88 | EZH2 (0.65) | EZH2 | |
| SCHEMBL16402544 | 0.86 | EZH2 (0.64) | EZH2 | |
| SCHEMBL17891368 | 0.86 | EZH2 (0.64) | EZH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015010049-A1 | SUBSTITUTED BENZENE COMPOUNDS | Epizyme, Inc. (US) | 2015-01-22 | — | — | WO | disclosed |