Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN3 | Q9H6Z9 | 7/20 | 0.52 |
| ▸ | EGLN1 | Q9GZT9 | 6/20 | 0.46 |
| ▸ | EGLN2 | Q96KS0 | 4/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.44 |
| ▸ | GSK3B | P49841 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12727518 | 0.91 | EGLN3 (0.56) | EGLN3EGLN1EGLN2HIF1A | |
| SCHEMBL1642203 | 0.87 | EGLN3 (0.54) | EGLN3EGLN1EGLN2HIF1A | |
| SCHEMBL1640806 | 0.86 | EGLN3 (0.53) | EGLN3EGLN1EGLN2HIF1A | |
| SCHEMBL1641853 | 0.86 | EGLN3 (0.53) | EGLN3EGLN1EGLN2HIF1A | |
| SCHEMBL1640375 | 0.86 | EGLN3 (0.53) | EGLN3EGLN1EGLN2HIF1A | |
| SCHEMBL1642773 | 0.85 | EGLN3 (0.51) | EGLN3EGLN1EGLN2HIF1A | |
| SCHEMBL1641696 | 0.85 | EGLN3 (0.51) | EGLN3EGLN1EGLN2HIF1A | |
| SCHEMBL1640476 | 0.85 | EGLN3 (0.65) | EGLN3EGLN1EGLN2HIF1A | |
| SCHEMBL1641915 | 0.85 | EGLN3 (0.55) | EGLN3EGLN1EGLN2HIF1A | |
| SCHEMBL1642739 | 0.84 | EGLN3 (0.53) | EGLN3EGLN1EGLN2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110098324-A1 | PROLYL HYDROXYLASE INHIBITORS | GLAXOSMITHKLINE LLC | 2011-04-28 | — | — | US | disclosed |
| US-20110098324-A1 | PROLYL HYDROXYLASE INHIBITORS | GLAXOSMITHKLINE LLC | 2011-04-28 | — | — | US | disclosed |
| US-20110098324-A1 | PROLYL HYDROXYLASE INHIBITORS | GLAXOSMITHKLINE LLC | 2011-04-28 | — | — | US | disclosed |
| WO-2009158315-A1 | PROLYL HYDROXYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-12-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098324-A1 | PROLYL HYDROXYLASE INHIBITORS | HIF1AN, EGLN2, EGLN3 | EGLN3 3/4885EGLN1 6/4885EGLN2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.