SCHEMBL16408323

SCHEMBL16408323

CCOc1ccc2cccc(-c3c4ccccc4c(-c4ccccc4)c4ccccc34)c2c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTK P33981 1/20 0.45
SMN1; SMN2 Q16637 4/20 0.43
TP53 P04637 3/20 0.43
MTNR1A P48039 2/20 0.43
CNR1 P21554 1/20 0.42
CNR2 P34972 1/20 0.42
GPR55 Q9Y2T6 1/20 0.42
KDM4E B2RXH2 4/20 0.41
LMNA P02545 4/20 0.41
ALDH1A1 P00352 3/20 0.41
HPGD P15428 3/20 0.41
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
HSD17B10 Q99714 2/20 0.41
USP2 O75604 1/20 0.41
MAPT P10636 1/20 0.41
TSHR P16473 1/20 0.41
NFKB1 P19838 1/20 0.41
NFKB2 Q00653 1/20 0.41
RELA Q04206 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16408380 0.89 SMN1; SMN2 (0.43) TTKSMN1; SMN2TP53CNR1CNR2
SCHEMBL16408420 0.87 TTK (0.39) TTKSMN1; SMN2TP53MTNR1ACNR1
SCHEMBL5098645 0.82 TTK (0.54) TTKSMN1; SMN2TP53CNR1CNR2
SCHEMBL10017298 0.79 SMN1; SMN2 (0.49) SMN1; SMN2TP53CNR1CNR2GPR55
SCHEMBL16408424 0.78 ESR1 (0.37) SMN1; SMN2TP53KDM4EALDH1A1HPGD
SCHEMBL30662422 0.77 SMN1; SMN2 (0.57) TTKSMN1; SMN2TP53KDM4ELMNA
SCHEMBL19583380 0.77 KMT2A (0.50) TTKTP53MTNR1AKDM4EALDH1A1
SCHEMBL27847547 0.77 FGFR1 (0.50) SMN1; SMN2TP53KDM4ENPC1RAB9A
SCHEMBL27864700 0.77 CDC25A (0.55) SMN1; SMN2TP53KDM4ELMNAALDH1A1
SCHEMBL30963915 0.77 TP53 (0.51) SMN1; SMN2TP53KDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015009076-A1 A COMBINATION OF A DOPANT COMPOUND AND A HOST COMPOUND AND AN ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2015-01-22 WO disclosed