Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 3/20 | 0.69 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.69 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.69 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.69 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.69 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.69 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.69 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16409814 | 0.84 | HDAC3 (0.63) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL16398143 | 0.83 | HDAC3 (0.67) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL11603568 | 0.82 | PDE3B (0.57) | CYP3A4CYP2C9ALDH1A1SMN1; SMN2PDE3B | |
| SCHEMBL16409848 | 0.82 | HDAC1 (1.00) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL16409843 | 0.82 | HDAC1 (1.00) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL16409825 | 0.82 | HDAC3 (0.82) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL16409824 | 0.81 | HDAC3 (0.74) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL16409769 | 0.80 | HDAC3 (0.67) | HDAC3HDAC4HDAC1HDAC2HDAC8 | |
| SCHEMBL11283742 | 0.80 | PDE3B (0.58) | CYP3A4CYP2C9ALDH1A1SMN1; SMN2PDE3B | |
| SCHEMBL16409816 | 0.80 | HDAC3 (0.71) | HDAC3HDAC4HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014196328-A1 | HYDROXAMIC ACID DERIVATIVE OR SALT THEREOF | 日本理化学工業株式会社 (JP) | 2014-12-11 | — | — | WO | disclosed |