Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.52 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27929864 | 0.87 | PARP10 (0.49) | PARP10PARP15TDP1PDE4APDE4D | |
| SCHEMBL14901056 | 0.81 | PARP10 (0.55) | PARP10PARP15FFAR4 | |
| SCHEMBL1697560 | 0.81 | PARP15 (0.52) | PARP10PARP15TDP1PDE4APDE4D | |
| SCHEMBL10187096 | 0.81 | PARP15 (0.52) | PARP10PARP15TDP1PDE4APDE4D | |
| SCHEMBL29040215 | 0.80 | PARP10 (0.48) | PARP10PARP15TDP1FFAR4 | |
| SCHEMBL22479881 | 0.80 | PARP10 (0.48) | PARP10PARP15FFAR4 | |
| SCHEMBL30495513 | 0.80 | PARP10 (0.48) | PARP10PARP15TDP1FFAR4 | |
| SCHEMBL24685887 | 0.78 | NQO1 (0.48) | FFAR4FFAR1 | |
| SCHEMBL16900529 | 0.78 | CA12 (0.42) | PARP10PARP15TDP1 | |
| SCHEMBL9223680 | 0.77 | PARP10 (0.49) | PARP10PARP15FFAR4FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2609065-B1 | PROCESSES FOR PRODUCING 1-BROMO-2 (CYCLOPROPYL METHOXY)-5 FLUORO-4- METHOXYBENZENE | ALBEMARLE CORP (US) | 2015-07-08 | — | — | EP | claimed |
| EP-2609065-A1 | PROCESSES FOR PRODUCING 1-BROMO-2 (CYCLOPROPYL METHOXY)-5 FLUORO-4- METHOXYBENZENE | Albemarle Corporation (US) | 2013-07-03 | — | — | EP | claimed |
| US-20130109887-A1 | PROCESSES FOR PRODUCING 1-BROMO-2- (CYCLOPROPYL METHOXY)-5-FLUORO-4-METHOXYBENZENE | ALBERMARLE CORPORATION (US) | 2013-05-02 | — | — | US | claimed |
| WO-2012027134-A1 | PROCESSES FOR PRODUCING 1-BROMO-2 (CYCLOPROPYL METHOXY)-5 FLUORO-4- METHOXYBENZENE | ALBEMARLE CORPORATION (US) | 2012-03-01 | — | — | WO | claimed |
| EP-2609065-B1 | PROCESSES FOR PRODUCING 1-BROMO-2 (CYCLOPROPYL METHOXY)-5 FLUORO-4- METHOXYBENZENE | ALBEMARLE CORP (US) | 2015-07-08 | — | — | EP | disclosed |
| EP-2609065-A1 | PROCESSES FOR PRODUCING 1-BROMO-2 (CYCLOPROPYL METHOXY)-5 FLUORO-4- METHOXYBENZENE | Albemarle Corporation (US) | 2013-07-03 | — | — | EP | disclosed |
| US-20130109887-A1 | PROCESSES FOR PRODUCING 1-BROMO-2- (CYCLOPROPYL METHOXY)-5-FLUORO-4-METHOXYBENZENE | ALBERMARLE CORPORATION (US) | 2013-05-02 | — | — | US | disclosed |
| US-20130109887-A1 | PROCESSES FOR PRODUCING 1-BROMO-2- (CYCLOPROPYL METHOXY)-5-FLUORO-4-METHOXYBENZENE | ALBERMARLE CORPORATION (US) | 2013-05-02 | — | — | US | disclosed |
| US-20130109887-A1 | PROCESSES FOR PRODUCING 1-BROMO-2- (CYCLOPROPYL METHOXY)-5-FLUORO-4-METHOXYBENZENE | ALBERMARLE CORPORATION (US) | 2013-05-02 | — | — | US | disclosed |
| WO-2012027134-A1 | PROCESSES FOR PRODUCING 1-BROMO-2 (CYCLOPROPYL METHOXY)-5 FLUORO-4- METHOXYBENZENE | ALBEMARLE CORPORATION (US) | 2012-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130109887-A1 | PROCESSES FOR PRODUCING 1-BROMO-2- (CYCLOPROPYL METHOXY)-5-FLUORO-4-METHOXYBENZENE | CYP4B1, CYP4X1, CYP1B1 | PARP10 847/4885PARP15 186/4885TDP1 3218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.