SCHEMBL164132

SCHEMBL164132

Cc1ccc2ccc3cc4ccccc4cc3c2c1C

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 9/20 0.52
CYP2A6 P11509 5/20 0.52
TSHR P16473 4/20 0.52
ALDH1A1 P00352 8/20 0.45
HSD17B10 Q99714 6/20 0.45
HPGD P15428 5/20 0.45
TDP1 Q9NUW8 2/20 0.45
CYP3A4 P08684 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
FYN P06241 2/20 0.42
ACHE P22303 2/20 0.42
AHR P35869 2/20 0.42
ERBB2 P04626 1/20 0.42
MAOA P21397 1/20 0.42
HIF1A Q16665 3/20 0.41
CYP1B1 Q16678 1/20 0.41
LCK P06239 1/20 0.40
ADORA3 P0DMS8 1/20 0.40
MAPT P10636 1/20 0.40
SLC6A2 P23975 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30361382 1.00 CYP1A2 (0.52) CYP1A2CYP2A6TSHRALDH1A1HSD17B10
SCHEMBL27939068 1.00 CYP1A2 (0.52) CYP1A2CYP2A6TSHRALDH1A1HSD17B10
SCHEMBL30892865 1.00 CYP1A2 (0.52) CYP1A2CYP2A6TSHRALDH1A1HSD17B10
SCHEMBL29726949 0.85 CYP1A2 (0.64) CYP1A2CYP2A6TSHRALDH1A1HSD17B10
SCHEMBL460085 0.85 CYP1A2 (0.64) CYP1A2CYP2A6TSHRALDH1A1HSD17B10
SCHEMBL9699573 0.83 CYP1A2 (0.61) CYP1A2CYP2A6TSHRALDH1A1HSD17B10
SCHEMBL686340 0.83 CYP1A2 (0.61) CYP1A2CYP2A6TSHRALDH1A1HSD17B10
SCHEMBL28539710 0.83 CYP1A2 (0.61) CYP1A2CYP2A6TSHRALDH1A1HSD17B10
SCHEMBL2003458 0.82 CYP1A2 (0.55) CYP1A2CYP2A6TSHRALDH1A1HSD17B10
Diethylamine SCHEMBL6932419 0.81 CYP1A2 (0.36) CYP1A2CYP2A6TSHRALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1544 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115850292-B Novel C-4 substituted coumarin compound and preparation method and application thereof 昆明医科大学 2024-04-12 CN claimed
US-20230131422-A1 LIGHT-ABSORBING EPOXY FILM AND MANUFACTURING METHOD THEREOF Hojeonable Inc. (KR) 2023-04-27 US claimed
CN-115850292-A Novel C-4 substituted coumarin compounds and preparation method and application thereof 昆明医科大学 2023-03-28 CN claimed
CN-114686435-A Preparation method of estrogen receptor positive mouse breast cancer cell strain 中山大学孙逸仙纪念医院 2022-07-01 CN claimed
CN-114271983-A Oral cancer animal model under arecoline background and molding method 中南大学湘雅医院 2022-04-05 CN claimed
US-20190110418-A1 PAPAYA WITH NOVEL TRAITS AND METHODS FOR PRODUCING SUCH PAPAYA PLANTS HORTIGENETICS RESEARCH (S.E. ASIA) LTD. (TH) 2019-04-18 US claimed
CN-106727492-A A kind of application of polymethoxyflavone on the medicine for preparing treatment cutaneous papilloma 黄冈师范学院 2017-05-31 CN claimed
CN-104001151-A Application of caerulin in preparing sensitizing preparation of medicaments for intervening in pancreatic cancer animal model UNIV FUDAN SHANGHAI CANCER CT 2014-08-27 CN claimed
JP-4350148-B2 2009-10-21 JP claimed
EP-1733056-A4 METHOD TO DETERMINE RESPONSIVENESS OF CANCER TO EPIDERMAL GROWTH FACTOR RECEPTOR TARGETING TREATMENTS GEN HOSPITAL CORP (US) 2009-08-12 EP claimed
US-20040053236-A1 Reverse genetic strategy for identifying functional mutations in genes of known sequences NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2004-03-18 US claimed
US-RE38392-E1 Method for identifying metastatic sequences BAYLOR COLLEGE OF MEDICINE 2004-01-20 US claimed
EP-0870057-B1 METHOD FOR IDENTIFYING METASTATIC SEQUENCES BAYLOR COLLEGE MEDICINE (US) 2003-09-24 EP claimed
US-20030003088-A1 Human pancreatic pluripotential stem cell line BOARD OF TRUSTEES OPERATING MICHIGAN STATE UNIVERSITY 2003-01-02 US claimed
WO-2001075167-A1 REVERSE GENETIC STRATEGY FOR IDENTIFYING FUNCTIONAL MUTATIONS IN GENES OF KNOWN SEQUENCE FRED HUTCHINSON CANCER RESEARCH CENTER (US) 2001-10-11 WO claimed
EP-0870057-A2 METHOD FOR IDENTIFYING METASTATIC SEQUENCES THE BAYLOR COLLEGE OF MEDICINE (US) 1998-10-14 EP claimed
US-5783182-A AMPLIFICATION; POLYMERASE CHAIN REACTION; CALIBRATION BAYLOR COLLEGE OF MEDICINE (US) 1998-07-21 US claimed
WO-1997018454-A9 METHOD FOR IDENTIFYING METASTATIC SEQUENCES 1997-07-17 WO claimed
WO-1997018454-A2 METHOD FOR IDENTIFYING METASTATIC SEQUENCES BAYLOR COLLEGE OF MEDICINE (US) 1997-05-22 WO claimed
WO-1994006413-A1 THERAPEUTIC ELEVATED LEVELS OF TRIMETHYLAMINE OXIDE THE BETH ISRAEL HOSPITAL ASSOCIATION (US) 1994-03-31 WO claimed