Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 18/20 | 0.68 |
| ▸ | FAP | Q12884 | 9/20 | 0.68 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.64 |
| ▸ | POU2F2 | P09086 | 1/20 | 0.64 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.64 |
| ▸ | POU2F1 | P14859 | 1/20 | 0.64 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.64 |
| ▸ | HRH2 | P25021 | 1/20 | 0.64 |
| ▸ | MC4R | P32245 | 1/20 | 0.64 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.64 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.64 |
| ▸ | GHSR | Q92847 | 1/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1772436 | 0.90 | DPP4 (0.63) | DPP4FAPCHRM1POU2F2ADORA3 | |
| SCHEMBL17036591 | 0.89 | DPP4 (0.72) | DPP4FAPCHRM1POU2F2ADORA3 | |
| SCHEMBL196303 | 0.88 | DPP4 (0.61) | DPP4FAPCHRM1POU2F2ADORA3 | |
| SCHEMBL196304 | 0.88 | DPP4 (0.61) | DPP4FAPCHRM1POU2F2ADORA3 | |
| SCHEMBL29801450 | 0.88 | DPP4 (0.61) | DPP4FAPCHRM1POU2F2ADORA3 | |
| SCHEMBL4474769 | 0.88 | DPP4 (0.61) | DPP4FAPCHRM1POU2F2ADORA3 | |
| SCHEMBL29801431 | 0.88 | DPP4 (0.61) | DPP4FAPCHRM1POU2F2ADORA3 | |
| SCHEMBL196984 | 0.88 | DPP4 (0.61) | DPP4FAPCHRM1POU2F2ADORA3 | |
| SCHEMBL12264211 | 0.88 | DPP4 (0.60) | DPP4FAPCHRM1POU2F2ADORA3 | |
| SCHEMBL18343936 | 0.87 | DPP4 (0.70) | DPP4FAPCHRM1POU2F2ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015011609-A1 | PROCESS FOR THE PREPARATION OF LINAGLIPTIN AND AN INTERMEDIATE THEREOF | RANBAXY LABORATORIES LIMITED (IN) | 2015-01-29 | — | — | WO | disclosed |
| WO-2015011609-A1 | PROCESS FOR THE PREPARATION OF LINAGLIPTIN AND AN INTERMEDIATE THEREOF | RANBAXY LABORATORIES LIMITED (IN) | 2015-01-29 | — | — | WO | disclosed |