Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.56 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.56 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.56 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.56 |
| ▸ | PDE4A | P27815 | 1/20 | 0.56 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.56 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.56 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.52 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | EGFR | P00533 | 3/20 | 0.47 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | PRKACA | P17612 | 1/20 | 0.47 |
| ▸ | LTK | P29376 | 1/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinazolinone SCHEMBL29709960 | 1.00 | PI4KA (0.56) | PI4KAPI4K2BPI4K2API4KBPDE4A | |
| Quinazolinone SCHEMBL4629529 | 0.98 | ADORA2A (0.55) | PI4KAPI4K2BPI4K2API4KBPDE4A | |
| Quinazolinone SCHEMBL28814393 | 0.90 | PI4KA (0.47) | PI4KAPI4K2BPI4K2API4KBPDE4A | |
| Quinazolinone SCHEMBL30077204 | 0.83 | PI4KA (0.39) | PI4KAPI4K2BPI4K2API4KBPDE4A | |
| SCHEMBL10751781 | 0.76 | PI4KA (0.50) | PI4KAPI4K2BPI4K2API4KBPDE4A | |
| SCHEMBL3075421 | 0.75 | ADORA2A (0.75) | PI4KAPI4K2BPI4K2API4KBPDE4A | |
| SCHEMBL8895855 | 0.74 | PI4KA (0.61) | PI4KAPI4K2BPI4K2API4KBPDE4A | |
| SCHEMBL30317618 | 0.73 | PARP1 (0.47) | ABCG2GAAEGFRMAP4K4ERBB2 | |
| SCHEMBL5453911 | 0.73 | EGFR (0.46) | ABCG2EGFRMAP4K4HTTGLA | |
| SCHEMBL1192531 | 0.73 | PARP1 (0.47) | ABCG2GAAEGFRMAP4K4ERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1089 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026106998-A1 | PROSTATE-SPECIFIC MEMBRANE ANTIGEN (PSMA)-TARGETED POLY(ADP-RIBOSE) POLYMERASE (PARP) INHIBITOR AND RELATED COMPOSITION AND METHOD OF USE | PURDUE RESEARCH FOUNDATION (US) | 2026-05-21 | — | — | WO | claimed |
| EP-4739310-A1 | ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE 1 (ENPP1) INHIBITOR COMBINATIONS AND USES THEREOF | Insilico Medicine IP Limited (HK) | 2026-05-13 | — | — | EP | claimed |
| CN-120195330-A | Construction method of characteristic spectrum of antifebrile dichroa and preparation thereof | 华润三九现代中药制药有限公司 | 2025-06-24 | — | — | CN | claimed |
| WO-2025007955-A1 | ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE 1 (ENPP1) INHIBITOR COMBINATIONS AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2025-01-09 | — | — | WO | claimed |
| WO-2024217502-A1 | METHIONINE ADENOSYLTRANSFERASE 2A (MAT2A) INHIBITOR COMBINATIONS AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2024-10-24 | — | — | WO | claimed |
| CN-117924252-A | Quinazoline-carbazole skeleton derivative and antidiabetic activity thereof | 西安医学院 | 2024-04-26 | — | — | CN | claimed |
| CN-116444445-A | Quinazolinone compound and preparation method thereof | 河北科技大学 | 2023-07-18 | — | — | CN | claimed |
| CN-116120242-B | Quick detection device for fenazaquin in tea, and preparation and application thereof | 佛山职业技术学院 | 2023-06-27 | — | — | CN | claimed |
| CN-116059229-B | Pharmaceutical composition for preventing and treating new coronavirus infection, and medicine and application thereof | 吉林华康药业股份有限公司 | 2023-06-20 | — | — | CN | claimed |
| CN-114315802-B | Quinazoline nitrogen-containing heterocyclic derivative, preparation method and application | 西安医学院 | 2023-06-16 | — | — | CN | claimed |
| US-5874444-A | CONTROLLING CELL AGING | GERON CORPORATION (US) | 1999-02-23 | — | — | US | claimed |
| WO-1998033786-A9 | ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS | — | 1998-12-30 | — | — | WO | claimed |
| WO-1998033786-A1 | ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1998-08-06 | — | — | WO | claimed |
| EP-0537600-B1 | An improved process for the preparation of 4-haloquinazolines | DOWELANCO (US) | 1997-07-16 | — | — | EP | claimed |
| CN-1121071-A | Synthesis and activity of 4-aryl oxime ether quinazoline compound | UNIV NANKAI (CN) | 1996-04-24 | — | — | CN | claimed |
| US-5214144-A | Halogenation of corresponding hydroxy derivative, simplified process | DOWELANCO (US) | 1993-05-25 | — | — | US | claimed |
| EP-0537600-A1 | An improved process for the preparation of 4-haloquinazolines | DOWELANCO (US) | 1993-04-21 | — | — | EP | claimed |
| EP-0380264-A2 | Halogenation process | DowElanco (US) | 1990-08-01 | — | — | EP | claimed |
| CN-1035825-A | Quinazoline derivant | LILLY CO ELI (US) | 1989-09-27 | — | — | CN | claimed |
| EP-0326329-A2 | Quinazoline derivatives | DowElanco (US) | 1989-08-02 | — | — | EP | claimed |