SCHEMBL16423933

SCHEMBL16423933

CC(C)NC(=O)Cn1c(-c2cccc(Cl)c2)nc2cc(B3OC(C)(C)C(C)(C)O3)ccc21

nearest known ligand 0.49

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AVPR1B P47901 5/20 0.49
AVPR1A P37288 15/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16423694 0.89 AVPR1B (0.43) AVPR1BAVPR1A
SCHEMBL17556399 0.87 AVPR1B (0.63) AVPR1BAVPR1A
SCHEMBL16442145 0.82 AVPR1B (0.55) AVPR1BAVPR1A
SCHEMBL16424034 0.81 AVPR1B (0.54) AVPR1BAVPR1A
SCHEMBL16424504 0.81 AVPR1B (0.41) AVPR1B
SCHEMBL15987999 0.79 AVPR1B (0.62) AVPR1B
SCHEMBL16452856 0.77 AVPR1B (0.62) AVPR1BAVPR1A
SCHEMBL16423784 0.77 AVPR1B (0.62) AVPR1BAVPR1A
SCHEMBL16423802 0.77 AVPR1B (0.42) AVPR1B
SCHEMBL3127811 0.76 AVPR1B (0.64) AVPR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150045551-A1 FUSED AZOLE DERIVATIVE TAISHO PHARMACEUTICAL CO., LTD (JP) 2015-02-12 US disclosed
US-20150045551-A1 FUSED AZOLE DERIVATIVE TAISHO PHARMACEUTICAL CO., LTD (JP) 2015-02-12 US disclosed
EP-2832722-A1 FUSED AZOLE DERIVATIVE Taisho Pharmaceutical Co., Ltd. (JP) 2015-02-04 EP disclosed
EP-2832722-A1 FUSED AZOLE DERIVATIVE Taisho Pharmaceutical Co., Ltd. (JP) 2015-02-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150045551-A1 FUSED AZOLE DERIVATIVE AVPR1B, AVPR1A, GRIN2B AVPR1B 1/4885AVPR1A 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.