Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PLEC | Q15149 | 1/20 | 0.34 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | IKBKB | O14920 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16425660 | 0.79 | MAOB (0.45) | NPC1RAB9AMAOBABCB1USP2 | |
| SCHEMBL16425628 | 0.79 | ABCB1 (0.53) | MAOBABCB1USP2ATMMEN1 | |
| SCHEMBL10013290 | 0.76 | PSMB8 (0.39) | NPC1RAB9AATMS1PR1S1PR3 | |
| SCHEMBL16425637 | 0.73 | POLB (0.39) | MAOBABCB1USP2ATMMEN1 | |
| SCHEMBL25274069 | 0.73 | MEN1 (0.40) | ABCB1USP2ATMMEN1KMT2A | |
| SCHEMBL13425726 | 0.72 | NPC1 (0.47) | NPC1RAB9AMEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL31237595 | 0.72 | S1PR1 (0.33) | NPC1RAB9AUSP2ATMMEN1 | |
| SCHEMBL21648620 | 0.71 | ABCB1 (0.57) | NPC1RAB9AABCB1USP2ATM | |
| SCHEMBL21648600 | 0.70 | MEN1 (0.43) | USP2ATMMEN1KMT2APOLB | |
| SCHEMBL17754037 | 0.70 | MEN1 (0.50) | USP2ATMMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9335323-B2 | Method for sorting of pluripotent cells | KYOTO UNIVERSITY (JP) | 2016-05-10 | — | — | US | disclosed |
| US-20150031062-A1 | METHOD FOR SORTING OF PLURIPOTENT CELLS | KYOTO UNIVERSITY (JP) | 2015-01-29 | — | — | US | disclosed |