Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 2/20 | 0.77 |
| ▸ | BRAF | P15056 | 2/20 | 0.57 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.49 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | BCL2 | P10415 | 2/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.48 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.48 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13510524 | 0.89 | EP300 (0.72) | EP300BRAFHSD11B1MCL1MEN1 | |
| SCHEMBL13510387 | 0.87 | EP300 (1.00) | EP300BRAFHSD11B1MCL1MEN1 | |
| SCHEMBL13510523 | 0.86 | EP300 (0.67) | EP300BRAFHSD11B1MCL1MEN1 | |
| SCHEMBL13510519 | 0.85 | EP300 (0.77) | EP300BRAFHSD11B1MCL1MEN1 | |
| SCHEMBL13510382 | 0.84 | EP300 (0.80) | EP300BRAFHSD11B1MCL1MEN1 | |
| SCHEMBL13510376 | 0.84 | EP300 (0.80) | EP300BRAFHSD11B1MCL1MEN1 | |
| SCHEMBL13510381 | 0.83 | EP300 (0.70) | EP300BRAFHSD11B1MCL1MEN1 | |
| SCHEMBL13510421 | 0.82 | EP300 (0.69) | EP300BRAFHSD11B1MEN1KMT2A | |
| SCHEMBL13510452 | 0.82 | EP300 (0.69) | EP300BRAFHSD11B1MCL1MEN1 | |
| SCHEMBL13510521 | 0.82 | EP300 (0.68) | EP300BRAFHSD11B1MCL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150031714-A1 | METHODS AND COMPOSITIONS FOR PREVENTION OF ALLERGIC REACTION | BAYLOR COLLEGE OF MEDICINE | 2015-01-29 | — | — | US | disclosed |
| US-20150031714-A1 | METHODS AND COMPOSITIONS FOR PREVENTION OF ALLERGIC REACTION | BAYLOR COLLEGE OF MEDICINE | 2015-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150031714-A1 | METHODS AND COMPOSITIONS FOR PREVENTION OF ALLERGIC REACTION | JAK2, STAT3, STAT6 | EP300 95/4885BRAF 1379/4885HSD11B1 1764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.