SCHEMBL16429657

SCHEMBL16429657

COc1ccc(OC(=O)C2CCC(C(=O)Oc3ccc(O)cc3)CC2)cc1

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.59
HTT P42858 2/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
ELANE P08246 2/20 0.53
LTA4H P09960 1/20 0.50
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
MEN1 O00255 1/20 0.50
MAPT P10636 1/20 0.50
ESR2 Q92731 1/20 0.50
GAA P10253 2/20 0.47
PKM P14618 2/20 0.47
POLB P06746 2/20 0.46
APP P05067 1/20 0.46
ATM Q13315 1/20 0.46
P4HB P07237 1/20 0.45
HPGD P15428 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19020578 1.00 KMT2A (0.59) KMT2AHTTSMN1; SMN2TDP1ELANE
SCHEMBL12536537 0.93 KMT2A (0.68) KMT2AHTTSMN1; SMN2TDP1ELANE
SCHEMBL3760925 0.93 KMT2A (0.68) KMT2AHTTSMN1; SMN2TDP1ELANE
SCHEMBL27694951 0.91 KMT2A (0.70) KMT2AHTTSMN1; SMN2TDP1ELANE
SCHEMBL4544901 0.91 KMT2A (0.70) KMT2AHTTSMN1; SMN2TDP1ELANE
SCHEMBL19000887 0.91 KMT2A (0.70) KMT2AHTTSMN1; SMN2TDP1ELANE
SCHEMBL20045190 0.91 KMT2A (0.70) KMT2AHTTSMN1; SMN2TDP1ELANE
SCHEMBL25870585 0.88 KMT2A (0.61) KMT2AHTTSMN1; SMN2TDP1ELANE
SCHEMBL8361962 0.87 KMT2A (0.56) KMT2AHTTSMN1; SMN2TDP1ELANE
SCHEMBL23720977 0.86 SMN1; SMN2 (0.59) KMT2AHTTSMN1; SMN2TDP1ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170190972-A1 LIQUID CRYSTAL DISPLAY DEVICE SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2017-07-06 US disclosed
US-9599759-B2 Patterned polarizing film and its production process SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-03-21 US disclosed
US-9599829-B2 Birefringent lens material for stereoscopic image display device and method for producing birefringent lens for stereoscopic image display device DIC CORPORATION (JP) 2017-03-21 US disclosed
US-20170073581-A1 MIXTURE THAT INCLUDES COMPOUND CONTAINING MESOGENIC GROUP DIC CORPORATION (JP) 2017-03-16 US disclosed
US-9540567-B2 Polymerizable liquid crystal composition and optically anisotropic body JNC CORPORATION (JP) 2017-01-10 US disclosed
US-20160369166-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION AND OPTICAL ANISOTROPICAL BODY THEREOF JNC CORPORATION (JP) 2016-12-22 US disclosed
US-20160370626-A1 LIQUID CRYSTAL DISPLAY DEVICE DIC CORPORATION (JP) 2016-12-22 US disclosed
US-20160289562-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION AND OPTICALLY ANISOTROPIC BODY JNC CORPORATION (JP) 2016-10-06 US disclosed
US-20150301251-A1 PATTERNED POLARIZING FILM AND ITS PRODUCTION PROCESS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-22 US disclosed
US-20150062505-A1 OPTICALLY ANISOTROPIC SHEET SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-03-05 US disclosed
US-20150030973-A1 BIREFRINGENT LENS MATERIAL FOR STEREOSCOPIC IMAGE DISPLAY DEVICE AND METHOD FOR PRODUCING BIREFRINGENT LENS FOR STEREOSCOPIC IMAGE DISPLAY DEVICE DIC CORPORATION (JP) 2015-01-29 US disclosed