Piperonyl Butoxide

Piperonyl Butoxide

SCHEMBL16431

CCCCOCCOCCOCc1cc2c(cc1CCC)OCO2.[Ti]

nearest known ligand 0.97

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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The experimentally established mechanism targets of Piperonyl Butoxide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.97
ALDH1A1 P00352 4/20 0.97
TSHR P16473 1/20 0.97
HPGD P15428 2/20 0.44
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
CYP1A2 P05177 3/20 0.37
CYP2D6 P10635 3/20 0.37
CYP2C19 P33261 3/20 0.37
CYP2C9 P11712 2/20 0.37
SMN1; SMN2 Q16637 3/20 0.36
RAB9A P51151 2/20 0.36
KDM4E B2RXH2 1/20 0.36
MAPT P10636 1/20 0.36
SCN1A P35498 1/20 0.35
SCN2A Q99250 1/20 0.35
SCN3A Q9NY46 1/20 0.35
HTT P42858 2/20 0.34
MAOB P27338 2/20 0.34
MAOA P21397 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Piperonyl Butoxide SCHEMBL9066646 0.99 CYP3A4 (0.94) CYP3A4ALDH1A1TSHRHPGDMEN1
Piperonyl Butoxide SCHEMBL8511783 0.99 CYP3A4 (0.94) CYP3A4ALDH1A1TSHRHPGDMEN1
Piperonyl Butoxide SCHEMBL2997422 0.99 CYP3A4 (0.94) CYP3A4ALDH1A1TSHRHPGDMEN1
Piperonyl Butoxide SCHEMBL5490 0.98 CYP3A4 (1.00) CYP3A4ALDH1A1TSHRHPGDMEN1
SCHEMBL9958244 0.98 CYP3A4 (1.00) CYP3A4ALDH1A1TSHRHPGDMEN1
Piperonyl Butoxide SCHEMBL29386186 0.98 CYP3A4 (1.00) CYP3A4ALDH1A1TSHRHPGDMEN1
Piperonyl Butoxide SCHEMBL6561910 0.98 CYP3A4 (1.00) CYP3A4ALDH1A1TSHRHPGDMEN1
Piperonyl Butoxide SCHEMBL1517385 0.98 CYP3A4 (1.00) CYP3A4ALDH1A1TSHRHPGDMEN1
Piperonyl Butoxide SCHEMBL4809313 0.97 CYP3A4 (0.97) CYP3A4ALDH1A1TSHRHPGDMEN1
Piperonyl Butoxide SCHEMBL11895741 0.97 CYP3A4 (0.97) CYP3A4ALDH1A1TSHRHPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 10812 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026087201-A1 PROCESS FOR POLYBUTYLENE TEREPHTHALATE PRODUCTION SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2026-04-30 WO claimed
US-20260115685-A1 CARBON BLOCK IMPREGNATED WITH TITANIUM (HYDR)OXIDES UNIV ARIZONA STATE (US) 2026-04-30 US claimed
US-20260116902-A1 NOVEL COMPOUND AS FUNCTIONAL ANTAGONIST FOR S1PR1 AND S1PR4 NEXTGEN BIOSCIENCE CO., LTD. (KR) 2026-04-30 US claimed
US-20260109810-A1 TRANSIENT COPOLYMERS, PREPARATION METHODS THEREOF, AND ARTICLES COMPRISING SAID TRANSIENT COPOLYMERS B4PLASTICS BV (BE) 2026-04-23 US claimed
EP-4212569-B1 METHOD FOR PREPARING BIODEGRADABLE POLYMER COMPOSITE AND BIODEGRADABLE POLYMER COMPOSITE LG CHEMICAL LTD (KR) 2026-04-08 EP claimed
US-20260078260-A1 NEAR-INFRARED REFLECTIVE CARBON BLACK BIRLA CARBON U S A (US) 2026-03-19 US claimed
US-12577423-B2 Metallic nanoparticle composition and method of dispensing metallic nanoparticle composition XTPL S.A. (PL) 2026-03-17 US claimed
EP-4707241-A1 METHOD FOR GROWTH OF LAYERED TRANSITION METAL SULFIDES OF TITANIUM OR TANTALUM Universität Hamburg KöR (DE) 2026-03-11 EP claimed
US-12570794-B2 Method for producing biodegradable polymer complex and biodegradable polymer complex LG CHEM, LTD. (KR) 2026-03-10 US claimed
EP-4702099-A1 PAINT WITH LOW LIGHT REFLECTIVITY AND LOW FOGGING Surrey Nanosystems Limited (GB) 2026-03-04 EP claimed
EP-0237640-A2 Method for production of ceramic composition MITSUBISHI MINING & CEMENT CO., LTD. (JP) 1987-09-23 EP claimed
CN-87100132-A Ethene high temperature (being total to) polymerization catalyst system 1987-09-02 CN claimed
EP-0233355-A2 Coated or laminated comosites PPG INDUSTRIES, INC. (US) 1987-08-26 EP claimed
EP-0203481-A2 Article comprising a rigid polymeric substrate and a coating, with a silicate-titanate copolymer as a primer between said polymeric substrate and said coating PPG INDUSTRIES, INC. (US) 1986-12-03 EP claimed
EP-0107700-A4 METHOD FOR FABRICATING CERAMIC MATERIALS. WESTERN ELECTRIC CO (US) 1986-05-16 EP claimed
US-4499262-A RAPID POLYMERIZATION; FOOD AND COSMETICS PACKAGING; BOTTLES; MOLDINGS EASTMAN KODAK COMPANY (US) 1985-02-12 US claimed
EP-0107700-A1 METHOD FOR FABRICATING CERAMIC MATERIALS. WESTERN ELECTRIC CO (US) 1984-05-09 EP claimed
WO-1983003823-A1 METHOD FOR FABRICATING CERAMIC MATERIALS WESTERN ELECTRIC COMPANY, INC. (US) 1983-11-10 WO claimed
US-4282092-A TITANIA-ALUMINA HITACHI, LTD. (JP) 1981-08-04 US claimed
US-3962189-A PROCESS AND CATALYST-INHIBITOR SYSTEMS FOR PREPARING SYNTHETIC LINEAR POLYESTERS EASTMAN KODAK COMPANY (US) 1976-06-08 US claimed