Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 17/20 | 0.62 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1643890 | 0.89 | MAPK14 (0.51) | MAPK14 | |
| SCHEMBL1643104 | 0.88 | MAPK14 (0.48) | MAPK14CHRM4GRM5 | |
| SCHEMBL1642335 | 0.86 | MAPK14 (0.63) | MAPK14CHRM4GRM5 | |
| SCHEMBL1642475 | 0.85 | MAPK14 (0.60) | MAPK14CHRM4GRM5 | |
| SCHEMBL1643812 | 0.85 | MAPK14 (0.48) | MAPK14 | |
| SCHEMBL1641832 | 0.85 | MAPK14 (0.55) | MAPK14CHRM4 | |
| SCHEMBL1642327 | 0.83 | MAPK14 (0.58) | MAPK14CHRM4GRM5 | |
| SCHEMBL2078503 | 0.82 | KIT (0.44) | MAPK14CHRM4GRM5 | |
| SCHEMBL1643850 | 0.81 | MAPK14 (0.45) | MAPK14CHRM4GRM5 | |
| SCHEMBL1642240 | 0.81 | MAPK14 (0.68) | MAPK14CHRM4GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110098298-A1 | New Pyridin-3-Amine Derivatives | LABORATORIOS ALMIRALL, S.A. (ES) | 2011-04-28 | — | — | US | claimed |
| US-20110098298-A1 | New Pyridin-3-Amine Derivatives | LABORATORIOS ALMIRALL, S.A. (ES) | 2011-04-28 | — | — | US | disclosed |
| EP-1987005-A2 | NEW PYRIDIN-3-AMINE DERIVATIVES | Laboratorios Almirall, S.A. (ES) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007096072-A2 | NEW PYRIDIN-3-AMINE DERIVATIVES | LABORATORIOS ALMIRALL, S.A. (ES) | 2007-08-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098298-A1 | New Pyridin-3-Amine Derivatives | MAPK1, MAP4K2, MAPK3 | MAPK14 33/4885CHRM4 1708/4885GRM5 898/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.