Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16518681 | 1.00 | EPHX2 (0.47) | EPHX2CYP1A2TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL18559671 | 0.98 | EPHX2 (0.46) | EPHX2CYP1A2TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL15506158 | 0.98 | EPHX2 (0.46) | EPHX2CYP1A2TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL15577026 | 0.98 | EPHX2 (0.46) | EPHX2CYP1A2TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL16518667 | 0.98 | EPHX2 (0.46) | EPHX2CYP1A2TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL15576980 | 0.98 | EPHX2 (0.49) | EPHX2CYP1A2TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL16234562 | 0.96 | EPHX2 (0.45) | EPHX2CYP1A2TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL15577029 | 0.96 | EPHX2 (0.45) | EPHX2CYP1A2TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL15827182 | 0.96 | EPHX2 (0.45) | EPHX2CYP1A2TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL15576967 | 0.96 | EPHX2 (0.45) | EPHX2CYP1A2TDP1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8946241-B2 | Tyrosine kinase inhibitors | PRINCIPIA BIOPHARMA INC. (US) | 2015-02-03 | — | — | US | disclosed |