Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TACR1 | P25103 | 2/20 | 0.35 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2109384 | 1.00 | CA1 (0.42) | CA1CA2CA7CA9HTT | |
| SCHEMBL2622832 | 1.00 | CA1 (0.42) | CA1CA2CA7CA9HTT | |
| SCHEMBL2109381 | 1.00 | CA1 (0.42) | CA1CA2CA7CA9HTT | |
| SCHEMBL2109388 | 1.00 | CA1 (0.42) | CA1CA2CA7CA9HTT | |
| SCHEMBL1934779 | 0.90 | TDP1 (0.40) | CA1CA2CA7CA9HTT | |
| SCHEMBL1934778 | 0.90 | TDP1 (0.40) | CA1CA2CA7CA9HTT | |
| SCHEMBL14739550 | 0.86 | CA1 (0.45) | CA1CA2CA7CA9HTT | |
| SCHEMBL2109601 | 0.82 | TDP1 (0.44) | CA1CA2CA7CA9HTT | |
| SCHEMBL2622825 | 0.82 | TDP1 (0.44) | CA1CA2CA7CA9HTT | |
| SCHEMBL2109597 | 0.82 | TDP1 (0.44) | CA1CA2CA7CA9HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8946211-B2 | Fused aminodihydrothiazine derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2015-02-03 | — | — | US | disclosed |