⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9020016 | 1.00 | — | — | |
| SCHEMBL18849923 | 0.97 | EPHX2 (0.44) | — | |
| SCHEMBL19663557 | 0.97 | EPHX2 (0.44) | — | |
| SCHEMBL14621075 | 0.97 | EPHX2 (0.39) | — | |
| SCHEMBL23717800 | 0.84 | EPHX2 (0.32) | — | |
| SCHEMBL12442307 | 0.84 | EPHX2 (0.58) | — | |
| SCHEMBL7942810 | 0.84 | EPHX2 (0.58) | — | |
| SCHEMBL13921587 | 0.84 | EPHX2 (0.58) | — | |
| SCHEMBL10066213 | 0.84 | EPHX2 (0.37) | — | |
| SCHEMBL6459361 | 0.82 | CYP2C9 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4702022-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE | Halda Therapeutics Opco, Inc. (US) | 2026-03-04 | — | — | EP | disclosed |
| US-20260028338-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE | HALDA THERAPEUTICS OPCO INC (US) | 2026-01-29 | — | — | US | disclosed |
| US-20250270190-A1 | KIT INHIBITORS | BLUEPRINT MEDICINES CORPORATION | 2025-08-28 | — | — | US | disclosed |
| EP-4572755-A2 | CDK2 DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2025-06-25 | — | — | EP | disclosed |
| EP-4568946-A1 | MACROCYCLIC BCL6 DEGRADERS | Dana-Farber Cancer Institute, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| EP-4561999-A1 | TARGETED PROTEIN DEGRADATION OF PARP14 FOR USE IN THERAPY | Abbvie Operations Singapore Pte. Ltd. (SG) | 2025-06-04 | — | — | EP | disclosed |
| CN-116648248-B | Aromatic compound, pharmaceutical composition containing same and application thereof | 成都茵创园医药科技有限公司 | 2025-04-15 | — | — | CN | disclosed |
| CN-119585240-A | Macrocyclic BCL6 degrading agents | 丹娜-法伯癌症研究院 | 2025-03-07 | — | — | CN | disclosed |
| WO-2025022124-A2 | METHODS FOR DEPOLYMERISING AND REPOLYMERISING | Epoch Biodesign Ltd (GB) | 2025-01-30 | — | — | WO | disclosed |
| WO-2024217515-A1 | HETEROCYCLIC RING-SUBSTITUTED AROMATIC COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | 上海复宏汉霖生物技术股份有限公司 | 2024-10-24 | — | — | WO | disclosed |
| CN-1040426-C | Process for preparing diprotected 2,3-hydroxymethyl cyclobutanol | SQUIBB & SONS INC (US) | 1998-10-28 | — | — | CN | disclosed |
| CN-1036712-C | Process for preparing guanine-containing antiviral agents and purinyl salts useful in such process | SQUIBB & SONS INC (US) | 1997-12-17 | — | — | CN | disclosed |
| EP-0352013-B1 | Hydroxymethyl cyclobutyl purines | SQUIBB & SONS INC (US) | 1996-05-01 | — | — | EP | disclosed |
| US-5369098-A | Viricides | E. R. SQUIBB & SONS, INC. (US) | 1994-11-29 | — | — | US | disclosed |
| CN-1083813-A | Contain guanine antiviral agent the preparation method and be used for the purine salt of this method | SQUIBB & SONS INC (US) | 1994-03-16 | — | — | CN | disclosed |
| CN-1082025-A | 2 of two protections, the preparation method of 3-methylol cyclobutanol | SQUIBB & SONS INC (US) | 1994-02-16 | — | — | CN | disclosed |
| CN-1082025-A | 2 of two protections, the preparation method of 3-methylol cyclobutanol | SQUIBB & SONS INC (US) | 1994-02-16 | — | — | CN | disclosed |
| EP-0352013-A2 | Hydroxymethyl cyclobutyl purines | E.R. Squibb & Sons, Inc. (US) | 1990-01-24 | — | — | EP | disclosed |
| EP-0330992-A2 | Novel cyclobutane Derivatives, processes for their preparation and pharmaceutical compositions comprising them | Nippon Kayaku Kabushiki Kaisha (JP) | 1989-09-06 | — | — | EP | disclosed |
| US-4096129-A | Glutarate-containing polyesterpolyols, methods of preparation and polyurethane compositions derived therefrom | FABRIDYNE, INC. (US) | 1978-06-20 | — | — | US | disclosed |