Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | CDK9 | P50750 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17804252 | 0.84 | GRM2 (0.37) | GRM2XDHCYP3A4CYP2C9CYP1A2 | |
| SCHEMBL16437134 | 0.82 | GRM2 (0.39) | GRM2CYP3A4CYP2C9CYP1A2CYP2D6 | |
| SCHEMBL16384944 | 0.82 | CYP2A6 (0.34) | CYP3A4CYP2C9MAPTSMN1; SMN2 | |
| SCHEMBL16384931 | 0.80 | GRIN1 (0.34) | CYP3A4CYP2C9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL16385370 | 0.79 | PDE10A (0.33) | CYP3A4CYP2C9CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL16385116 | 0.78 | MRGPRX4 (0.36) | CYP3A4CYP2C9CYP2D6CYP2C19MAPK14 | |
| SCHEMBL16384935 | 0.77 | MAOB (0.33) | MAOB | |
| SCHEMBL16549556 | 0.76 | PDE5A (0.35) | CYP3A4CYP2D6CYP2C19MAPTGRIN2B | |
| SCHEMBL16384957 | 0.75 | MRGPRX4 (0.36) | POLBBRD4 | |
| SCHEMBL16385244 | 0.75 | MRGPRX4 (0.38) | CYP3A4CYP2C9MAPTSMN1; SMN2GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015016372-A1 | TETRAZOLINONE COMPOUND, AND USE THEREFOR | 住友化学株式会社 (JP) | 2015-02-05 | — | — | WO | disclosed |