Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | WEE1 | P30291 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 3/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
| ▸ | TEK | Q02763 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16154635 | 0.92 | TP53 (0.65) | TP53KDM4EALDH1A1HPGDTSHR | |
| SCHEMBL16447960 | 0.91 | TP53 (0.54) | TP53KDM4EALDH1A1HPGDTSHR | |
| SCHEMBL16454335 | 0.91 | TP53 (0.54) | TP53KDM4EALDH1A1HPGDTSHR | |
| SCHEMBL16454338 | 0.90 | TP53 (0.55) | TP53KDM4EALDH1A1HPGDTSHR | |
| SCHEMBL16446048 | 0.88 | TP53 (0.51) | TP53KDM4EALDH1A1HSD17B10G6PD | |
| SCHEMBL16454748 | 0.86 | TP53 (0.62) | TP53KDM4EALDH1A1HPGDTSHR | |
| SCHEMBL16625998 | 0.86 | TP53 (0.62) | TP53ALDH1A1NPC1WEE1CNR2 | |
| SCHEMBL16454764 | 0.85 | TP53 (0.61) | TP53KDM4EHSD17B10NPC1CNR2 | |
| SCHEMBL12608711 | 0.84 | TP53 (0.43) | TP53KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL16454348 | 0.84 | SMN1; SMN2 (0.46) | TP53G6PDWEE1HIF1AKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015020553-A1 | CARBAZOLE COMPOUNDS AND METHODS OF USING SAME | OBSCHESTVO S OGRANICHENNOY OTVETSTVENNOST'YU "PANACELA LABS" (RU) | 2015-02-12 | — | — | WO | disclosed |
| WO-2015020553-A1 | CARBAZOLE COMPOUNDS AND METHODS OF USING SAME | OBSCHESTVO S OGRANICHENNOY OTVETSTVENNOST'YU "PANACELA LABS" (RU) | 2015-02-12 | — | — | WO | disclosed |