Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 8/20 | 0.64 |
| ▸ | WEE1 | P30291 | 6/20 | 0.51 |
| ▸ | KDR | P35968 | 2/20 | 0.50 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.48 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.48 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 3/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.47 |
| ▸ | KIT | P10721 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16454990 | 0.85 | CSF1R (0.59) | CSF1RWEE1KDREGFRFGFR4 | |
| SCHEMBL16447797 | 0.85 | CSF1R (0.60) | CSF1RWEE1KDREGFRFGFR4 | |
| SCHEMBL16446241 | 0.83 | WEE1 (0.73) | CSF1RWEE1KDREGFRFGFR4 | |
| SCHEMBL14875912 | 0.80 | WEE1 (0.67) | CSF1RWEE1KDREGFRFGFR4 | |
| SCHEMBL31557031 | 0.80 | WEE1 (0.67) | CSF1RWEE1KDREGFRFGFR4 | |
| SCHEMBL3529229 | 0.79 | CSF1R (0.79) | CSF1RWEE1SRCNTRK1KIT | |
| SCHEMBL4572823 | 0.79 | CSF1R (0.84) | CSF1RWEE1SRCNTRK1KIT | |
| SCHEMBL3528195 | 0.78 | CSF1R (1.00) | CSF1RWEE1SRCNTRK1KIT | |
| SCHEMBL10192654 | 0.76 | CDK4 (0.72) | KDREGFRFGFR4FGFR1FGFR2 | |
| SCHEMBL3971155 | 0.76 | EGFR (0.65) | WEE1KDREGFRFGFR4FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015019037-A1 | PHARMACEUTICAL COMPOUNDS | ALMAC DISCOVERY LIMITED (GB) | 2015-02-12 | — | — | WO | disclosed |