Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16446288 | 0.83 | NPC1 (0.30) | NPC1PKMRAB9ASMN1; SMN2 | |
| SCHEMBL16446189 | 0.81 | — | — | |
| SCHEMBL16454207 | 0.80 | — | — | |
| SCHEMBL16446128 | 0.77 | — | — | |
| SCHEMBL16446135 | 0.71 | BCL2A1 (0.36) | SMN1; SMN2 | |
| SCHEMBL21517789 | 0.69 | CCR9 (0.31) | — | |
| SCHEMBL20299046 | 0.67 | USP2 (0.37) | — | |
| SCHEMBL16446502 | 0.66 | NPC1 (0.43) | NPC1PKMRAB9ASMN1; SMN2 | |
| SCHEMBL21517802 | 0.66 | — | — | |
| SCHEMBL19997922 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9605004-B2 | Chemical compounds | SYNGENTA LIMITED (GB) | 2017-03-28 | — | — | US | disclosed |
| US-9605004-B2 | Chemical compounds | SYNGENTA LIMITED (GB) | 2017-03-28 | — | — | US | disclosed |
| US-9605004-B2 | Chemical compounds | SYNGENTA LIMITED (GB) | 2017-03-28 | — | — | US | disclosed |
| US-20160168126-A1 | CHEMICAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2016-06-16 | — | — | US | disclosed |
| US-20160168126-A1 | CHEMICAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2016-06-16 | — | — | US | disclosed |
| US-20160168126-A1 | CHEMICAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2016-06-16 | — | — | US | disclosed |
| EP-3030082-A1 | PYRAZOLYL PYRROLINONES AND THEIR USE AS HERBICIDES | Syngenta Participations AG (CH) | 2016-06-15 | — | — | EP | disclosed |
| EP-3030080-A1 | PYRAZOLYL PYRROLINONES AND THEIR USE AS HERBICIDES | Syngenta Participations AG (CH) | 2016-06-15 | — | — | EP | disclosed |
| US-20160159819-A1 | CHEMICAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2016-06-09 | — | — | US | disclosed |
| US-20160159819-A1 | CHEMICAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2016-06-09 | — | — | US | disclosed |
| US-20160159819-A1 | CHEMICAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2016-06-09 | — | — | US | disclosed |
| WO-2015018433-A1 | PYRAZOLYL PYRROLINONES AND THEIR USE AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-02-12 | — | — | WO | disclosed |
| WO-2015018434-A1 | PYRAZOLYL PYRROLINONES AND THEIR USE AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-02-12 | — | — | WO | disclosed |
| WO-2015018433-A1 | PYRAZOLYL PYRROLINONES AND THEIR USE AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-02-12 | — | — | WO | disclosed |
| WO-2015018434-A1 | PYRAZOLYL PYRROLINONES AND THEIR USE AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-02-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160168126-A1 | CHEMICAL COMPOUNDS | RDX, CBR3, RRS1 | NPC1 4792/4885PKM 482/4885RAB9A 1739/4885 |
| US-20160159819-A1 | CHEMICAL COMPOUNDS | RDX, CBR3, RRS1 | NPC1 4797/4885PKM 458/4885RAB9A 1543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.