SCHEMBL164474

SCHEMBL164474

CCCCCCCCON1C(C)(C)CC(CCCCNc2ncnc(NCCCCC3CC(C)(C)N(OCCCCCCCC)C(C)(C)C3)n2)CC1(C)C

nearest known ligand 0.34

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MERTK Q12866 5/20 0.34
FLT3 P36888 3/20 0.34
TYRO3 Q06418 3/20 0.34
GAS6 Q14393 3/20 0.34
DNM2 P50570 5/20 0.34
NPSR1 Q6W5P4 2/20 0.33
KCNH3 Q9ULD8 2/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33
HRH4 Q9H3N8 1/20 0.32
CCNB2 O95067 1/20 0.32
CDK1 P06493 1/20 0.32
CCNB1 P14635 1/20 0.32
CCNB3 Q8WWL7 1/20 0.32
S1PR2 O95136 1/20 0.32
LMNA P02545 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8649938 0.93 KMT2A (0.37) MERTKFLT3TYRO3GAS6DNM2
SCHEMBL9428796 0.87 KMT2A (0.36) DNM2NPSR1KCNH3MAPTHTT
SCHEMBL9428534 0.87 KMT2A (0.36) DNM2NPSR1KCNH3MAPTHTT
SCHEMBL9429015 0.87 KMT2A (0.49) MERTKFLT3TYRO3GAS6DNM2
SCHEMBL9429500 0.87 KMT2A (0.49) DNM2NPSR1KCNH3MAPTHTT
SCHEMBL7456211 0.87 KMT2A (0.49) DNM2NPSR1KCNH3MAPTHTT
SCHEMBL9428382 0.87 KMT2A (0.49) MERTKFLT3TYRO3GAS6DNM2
SCHEMBL9428703 0.87 KMT2A (0.49) MERTKFLT3TYRO3GAS6DNM2
SCHEMBL9428099 0.87 KMT2A (0.36) DNM2NPSR1KCNH3MAPTHTT
SCHEMBL9428645 0.87 KMT2A (0.49) DNM2NPSR1KCNH3MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4201989-B1 POLYOLEFIN-BASED RESIN FOAMED PARTICLES AND POLYOLEFIN-BASED RESIN FOAM MOLDED ARTICLE KANEKA CORP (JP) 2025-08-06 EP disclosed
EP-4201989-A1 POLYOLEFIN-BASED RESIN FOAMED PARTICLES AND POLYOLEFIN-BASED RESIN FOAM MOLDED ARTICLE Kaneka Corporation (JP) 2023-06-28 EP disclosed
CN-114075354-A Polyolefin resin foamed particles and polyolefin resin foamed molded article thereof 株式会社钟化 2022-02-22 CN disclosed
US-10072128-B2 Polyolefin-based resin pre-expanded particles and polyolefin-based resin in-mold expansion molded article comprising polyolefin-based resin pre- expanded particles KANEKA CORPORATION (JP) 2018-09-11 US disclosed
EP-2611860-B1 EXPANDED POLYOLEFIN CONTAINING POWDERED ACTIVATED CARBON KANEKA BELGIUM NV (BE) 2018-08-08 EP disclosed
EP-2743295-B1 POLYOLEFIN RESIN FOAM PARTICLES AND IN-MOLD FOAMING MOLDED BODY OF SAME KANEKA CORP (JP) 2016-04-27 EP disclosed
US-9249281-B2 Polyolefin resin foam particles and in-mold foaming molded body of same KANEKA CORPORATION (JP) 2016-02-02 US disclosed
US-20150210815-A1 POLYOLEFIN-BASED RESIN PRE-EXPANDED PARTICLES AND POLYOLEFIN-BASED RESIN IN-MOLD EXPANSION MOLDED ARTICLE COMPRISING POLYOLEFIN-BASED RESIN PRE-EXPANDED PARTICLES KANEKA CORPORATION (JP) 2015-07-30 US disclosed
EP-2420533-B1 POLYOLEFIN RESIN PRE-EXPANDED PARTICLES AND POLYOLEFIN RESIN IN-MOLD EXPANSION-MOLDED ARTICLE COMPRISING POLYOLEFIN RESIN PRE-EXPANDED PARTICLES KANEKA CORP (JP) 2014-12-31 EP disclosed
US-20140171534-A1 POLYOLEFIN RESIN FOAM PARTICLES AND IN-MOLD FOAMING MOLDED BODY OF SAME KANEKA CORPORATION (JP) 2014-06-19 US disclosed
EP-2743295-A1 POLYOLEFIN RESIN FOAM PARTICLES AND IN-MOLD FOAMING MOLDED BODY OF SAME Kaneka Corporation (JP) 2014-06-18 EP disclosed
EP-2611860-A1 EXPANDED POLYOLEFIN CONTAINING POWDERED ACTIVATED CARBON Kaneka Belgium N.V. (BE) 2013-07-10 EP disclosed
US-20130158141-A1 EXPANDED POLYOLEFIN CONTAINING POWDERED ACTIVATED CARBON KANEKA BELGIUM N.V. (BE) 2013-06-20 US disclosed
WO-2012028953-A1 EXPANDED POLYOLEFIN CONTAINING POWDERED ACTIVATED CARBON KANEKA BELGIUM N.V. (BE) 2012-03-08 WO disclosed
EP-2420533-A1 POLYOLEFIN RESIN PRE-EXPANDED PARTICLES AND POLYOLEFIN RESIN IN-MOLD EXPANSION-MOLDED ARTICLE COMPRISING POLYOLEFIN RESIN PRE-EXPANDED PARTICLES Kaneka Corporation (JP) 2012-02-22 EP disclosed
US-20120037837-A1 POLYOLEFIN-BASED RESIN PRE-EXPANDED PARTICLES AND POLYOLEFIN-BASED RESIN IN-MOLD EXPANSION MOLDED ARTICLE COMPRISING POLYOLEFIN-BASED RESIN PRE-EXPANDED PARTICLES KANEKA CORPORATION (JP) 2012-02-16 US disclosed
EP-1454947-B1 FLAME RETARDANT POLYOLEFIN RESIN PRE-EXPANDED PARTICLES AND IN-MOLD FOAMED ARTICLES PREPARED THEREFROM KANEKA CORP (JP) 2010-02-17 EP disclosed
US-6822023-B2 MIXTURE CONTAINING STERIC HINDERED OXYAMINE COMPOUND KANEKA CORPORATION (JP) 2004-11-23 US disclosed
EP-1454947-A1 PRE−EXPANDED BEADS OF FLAME−RETARDANT POLYOLEFIN RESIN AND MOLDED OBJECT THEREOF BY IN−MOLD FOAMING KANEKA CORPORATION (JP) 2004-09-08 EP disclosed
US-20030105194-A1 Flame retardant polyolefin resin pre-expanded particles and in-mold foamed articles prepared therefrom KANEKA CORPORATION (JP) 2003-06-05 US disclosed