Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 20/20 | 0.63 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15558204 | 0.90 | SCN9A (0.68) | SCN9ASCN5A | |
| SCHEMBL16448617 | 0.89 | SCN9A (0.59) | SCN9ASCN5A | |
| SCHEMBL16448620 | 0.87 | SCN9A (0.55) | SCN9A | |
| SCHEMBL16448622 | 0.87 | SCN9A (0.68) | SCN9ASCN5A | |
| SCHEMBL15558549 | 0.87 | SCN9A (0.64) | SCN9ASCN5A | |
| SCHEMBL16448627 | 0.85 | SCN9A (0.66) | SCN9ASCN5A | |
| SCHEMBL17428505 | 0.84 | SCN9A (0.58) | SCN9ASCN5A | |
| SCHEMBL19064829 | 0.84 | SCN9A (0.58) | SCN9ASCN5A | |
| SCHEMBL15535926 | 0.83 | SCN9A (0.53) | SCN9ASCN5A | |
| SCHEMBL16448718 | 0.83 | SCN9A (0.67) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8952169-B2 | N-substituted benzamides and methods of use thereof | XENON PHARMACEUTICALS INC. (CA) | 2015-02-10 | — | — | US | disclosed |
| US-8952169-B2 | N-substituted benzamides and methods of use thereof | XENON PHARMACEUTICALS INC. (CA) | 2015-02-10 | — | — | US | disclosed |