SCHEMBL16448647

SCHEMBL16448647

CC(C)(C)OC(=O)c1cc(Cl)c(OC[C@]2(C)CC[C@H](C)CC2)cc1F

nearest known ligand 0.44

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 20/20 0.44
SCN5A Q14524 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15536886 0.90 SCN9A (0.53) SCN9ASCN5A
SCHEMBL15536884 0.90 SCN9A (0.53) SCN9ASCN5A
SCHEMBL17069392 0.89 SCN9A (0.50) SCN9ASCN5A
SCHEMBL16448612 0.88 SCN9A (0.48) SCN9ASCN5A
SCHEMBL15536473 0.87 SCN9A (0.47) SCN9ASCN5A
SCHEMBL16448648 0.87 SCN9A (0.56) SCN9ASCN5A
SCHEMBL16759216 0.84 SCN9A (0.43) SCN9ASCN5A
SCHEMBL28078760 0.84 SCN9A (0.41) SCN9ASCN5A
SCHEMBL15548824 0.84 SCN9A (0.43) SCN9ASCN5A
SCHEMBL16759069 0.82 SCN9A (0.42) SCN9ASCN5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8952169-B2 N-substituted benzamides and methods of use thereof XENON PHARMACEUTICALS INC. (CA) 2015-02-10 US disclosed