Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 18/20 | 0.70 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16448713 | 0.87 | SCN9A (0.76) | SCN9ASCN5A | |
| SCHEMBL15536732 | 0.86 | SCN9A (0.67) | SCN9ASCN5A | |
| SCHEMBL16449065 | 0.86 | SCN9A (0.55) | SCN9ASCN5A | |
| SCHEMBL16448631 | 0.86 | SCN9A (0.68) | SCN9ASCN5A | |
| SCHEMBL16448630 | 0.86 | SCN9A (0.68) | SCN9ASCN5A | |
| SCHEMBL15557688 | 0.86 | SCN9A (0.67) | SCN9ASCN5A | |
| SCHEMBL16448655 | 0.86 | SCN9A (0.67) | SCN9ASCN5A | |
| SCHEMBL16448653 | 0.86 | SCN9A (0.67) | SCN9ASCN5A | |
| SCHEMBL15557687 | 0.86 | SCN9A (0.67) | SCN9ASCN5A | |
| SCHEMBL16448613 | 0.84 | SCN9A (0.63) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8952169-B2 | N-substituted benzamides and methods of use thereof | XENON PHARMACEUTICALS INC. (CA) | 2015-02-10 | — | — | US | disclosed |
| US-8952169-B2 | N-substituted benzamides and methods of use thereof | XENON PHARMACEUTICALS INC. (CA) | 2015-02-10 | — | — | US | disclosed |