Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 20/20 | 0.66 |
| ▸ | GNA15 | P30679 | 1/20 | 0.53 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.53 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.53 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.53 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16448773 | 0.89 | FFAR1 (0.67) | FFAR1GNA15SLC10A1ABCC2SLCO1B3 | |
| SCHEMBL1688252 | 0.88 | FFAR1 (0.66) | FFAR1GNA15SLC10A1ABCC2SLCO1B3 | |
| SCHEMBL203930 | 0.88 | FFAR1 (0.69) | FFAR1GNA15SLC10A1ABCC2SLCO1B3 | |
| SCHEMBL27895903 | 0.86 | FFAR1 (0.60) | FFAR1 | |
| SCHEMBL27962432 | 0.86 | FFAR1 (0.63) | FFAR1GNA15SLC10A1ABCC2SLCO1B3 | |
| SCHEMBL16448792 | 0.86 | FFAR1 (0.69) | FFAR1GNA15SLC10A1ABCC2SLCO1B3 | |
| SCHEMBL30441627 | 0.83 | FFAR1 (0.61) | FFAR1GNA15SLC10A1ABCC2SLCO1B3 | |
| SCHEMBL15153514 | 0.83 | FFAR1 (0.78) | FFAR1GNA15SLC10A1ABCC2SLCO1B3 | |
| SCHEMBL27913199 | 0.82 | FFAR1 (0.59) | FFAR1 | |
| SCHEMBL16523399 | 0.82 | FFAR1 (0.65) | FFAR1GNA15SLC10A1ABCC2SLCO1B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105246875-A | Indane derivative, preparation method therefor, and pharmaceutical application thereof | SICHUAN HAISCO PHARMACEUTICAL CO LTD | 2016-01-13 | — | — | CN | disclosed |
| CN-104650031-A | Aromatic heterocyclic carboxylic acid derivative | KBP BIOSCIENCES CO LTD | 2015-05-27 | — | — | CN | disclosed |
| CN-103012343-B | Fused-ring derivative and preparation method thereof as well as application of fused-ring derivative in medicine | SHANGHAI HENGRUI PHARM CO LTD | 2015-04-08 | — | — | CN | disclosed |
| WO-2015032328-A1 | INDANE DERIVATIVE, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATION THEREOF | 四川海思科制药有限公司 (CN) | 2015-03-12 | — | — | WO | disclosed |
| US-8952185-B2 | Production method of optically active dihydrobenzofuran derivative | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-02-10 | — | — | US | disclosed |
| US-8952185-B2 | Production method of optically active dihydrobenzofuran derivative | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-02-10 | — | — | US | disclosed |
| CN-103012343-A | Fused-ring derivative and preparation method thereof as well as application of fused-ring derivative in medicine | SHANGHAI HENGRUI PHARM CO LTD | 2013-04-03 | — | — | CN | disclosed |