Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NEU1 | Q99519 | 15/20 | 0.63 |
| ▸ | NEU3 | Q9UQ49 | 10/20 | 0.63 |
| ▸ | NEU4 | Q8WWR8 | 5/20 | 0.63 |
| ▸ | NEU2 | Q9Y3R4 | 3/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10054708 | 1.00 | NEU1 (0.63) | NEU1NEU3NEU4NEU2 | |
| SCHEMBL10054918 | 1.00 | NEU1 (0.63) | NEU1NEU3NEU4NEU2 | |
| SCHEMBL16449133 | 1.00 | NEU1 (0.63) | NEU1NEU3NEU4NEU2 | |
| SCHEMBL10024191 | 0.86 | NEU1 (0.67) | NEU1NEU3NEU4NEU2 | |
| SCHEMBL17636054 | 0.84 | NEU1 (0.46) | NEU1NEU3NEU4NEU2 | |
| Neu5Ac2En SCHEMBL24387783 | 0.78 | NEU2 (1.00) | NEU1NEU3NEU4NEU2 | |
| Neu5Ac2En SCHEMBL13839147 | 0.78 | NEU2 (1.00) | NEU1NEU3NEU4NEU2 | |
| Neu5Ac2En SCHEMBL21125943 | 0.78 | NEU2 (1.00) | NEU1NEU3NEU4NEU2 | |
| Neu5Ac2En SCHEMBL22263416 | 0.78 | NEU2 (1.00) | NEU1NEU3NEU4NEU2 | |
| Neu5Ac2En SCHEMBL2619259 | 0.78 | NEU2 (1.00) | NEU1NEU3NEU4NEU2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427446-B1 | INHIBITORS OF SIALIDASE OR SIALIDASE-LIKE ENZYMES | NAT RES COUNCIL CANADA (CA) | 2016-03-30 | — | — | EP | disclosed |
| US-8952183-B2 | Inhibitors of sialidase or sialidase-like enzymes | NATIONAL RESEARCH COUNCIL OF CANADA | 2015-02-10 | — | — | US | disclosed |